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Dextromethorphan-bupropion relieves symptoms in major depressive disorder
Treatment with dextromethorphan-bupropion (AXS-05) significantly improves depressive symptoms relative to bupropion alone and is well tolerated in patients with major depression, results of a phase II trial have shown.
Dextromethorphan-bupropion relieves symptoms in major depressive disorder
13 Jul 2022Ozoralizumab shows therapeutic potential in rheumatoid arthritis
Treatment with the next-generation anti-TNFα antibody yields marked improvements in the signs and symptoms of rheumatoid arthritis in patients with inadequate response to methotrexate (MTX), while having an acceptable safety profile, as shown in the phase II/III OHZORA trial.
Ozoralizumab shows therapeutic potential in rheumatoid arthritis
13 Jul 2022Solithromycin safe, effective in paediatric community-acquired bacterial pneumonia
Treatment with intravenous or oral solithromycin is well-tolerated and leads to clinical improvement in most children and adolescents with community-acquired bacterial pneumonia (CABP), results of a recent study have shown.
Solithromycin safe, effective in paediatric community-acquired bacterial pneumonia
12 Jul 2022Camostat mesylate flops against SARS-CoV-2
The serine protease inhibitor camostat mesylate does not appear to be an effective antiviral agent in patients with early-phase COVID-19, having failed to stop SARS-CoV-2 in its tracks in a phase II trial.
Camostat mesylate flops against SARS-CoV-2
12 Jul 2022Isotretinoin does not hurt patients’ mental health, study says
While treatment with isotretinoin for acne is said to have a negative impact on mental health, its use appears to instead mitigate the excess psychiatric risk associated with treatment-resistant moderate-to-severe acne, as reported in a large study.
Isotretinoin does not hurt patients’ mental health, study says
11 Jul 2022Systematic endotracheal aspiration cuts antibiotic use for ventilator-related pneumonia
Being aware of bronchial colonization results in a decreased use of initial broad-spectrum antibiotic for ventilator-associated pneumonia (VAP) in the paediatric intensive care unit (PICU), reports a recent study.
Systematic endotracheal aspiration cuts antibiotic use for ventilator-related pneumonia
11 Jul 2022Is extended superior to standard antibiotic course in children hospitalized with CAP?
An extended antibiotic course appears to be not any better than a standard course at achieving clinical cure among children hospitalized with community-acquired pneumonia (CAP) and at risk of chronic respiratory illnesses at 4 weeks, a study has shown.