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Abiraterone plus prednisolone, enzalutamide a toss-up in castration-resistant prostate cancer
The combination of abiraterone plus prednisolone appears to have similar efficacy and safety as enzalutamide in the treatment of patients with nonmetastatic castration-resistant prostate cancer, according to a study.
Abiraterone plus prednisolone, enzalutamide a toss-up in castration-resistant prostate cancer
21 Dec 2023Add-on ribociclib continues to triumph in early breast cancer
Coming on the heels of the second interim analysis, the protocol-specified final invasive disease-free survival (iDFS) analysis of the phase III NATALEE trial continues to show a highly significant iDFS benefit with the combination of the CDK 4/6 inhibitor ribociclib and a nonsteroidal aromatase inhibitor (NSAI) in individuals with HR+/HER2- early breast cancer.
Add-on ribociclib continues to triumph in early breast cancer
20 Dec 2023Second-line CAR-T too costly for treatment of diffuse large B-cell lymphoma
Second-line treatment with axicabtagene ciloleucel (axi-cel) or lisocabtagene maraleucel (liso-cel) helps improve survival in high-risk patients with diffuse large B-cell lymphoma (DLBCL), but both therapies are expensive, a study has shown.
Second-line CAR-T too costly for treatment of diffuse large B-cell lymphoma
18 Dec 2023MONARCH 3 final OS data support abemaciclib-NSAI for HR+/HER2- advanced breast cancer
In the final overall survival (OS) analysis of the phase III MONARCH 3 trial, the combination of the CDK 4/6 inhibitor abemaciclib and a nonsteroidal aromatase inhibitor (NSAI) continued to show clinically meaningful signals as first-line (1L) treatment for HR+/HER2- advanced breast cancer.