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Polycythemia ups risk of MACE, VTE in men on testosterone therapy
Men receiving testosterone therapy (TT) who develop polycythemia are at greater risk for major adverse cardiovascular events (MACE) and venous thromboembolism (VTE) in the first year of therapy, according to a recent study.
Polycythemia ups risk of MACE, VTE in men on testosterone therapy
06 Jun 2022
Early ivermectin use does not confer benefit for COVID-19
In outpatients with an early diagnosis of COVID-19 at high risk for serious illness, treatment with the antiparasitic ivermectin did not reduce the incidence of hospital admission due to disease progression or of prolonged emergency department observation, findings from the TOGETHER trial suggest.
Early ivermectin use does not confer benefit for COVID-19
06 Jun 2022
Empagliflozin: A new dawn for heart failure treatment across the ejection fraction spectrum
Initially approved to improve glycaemic control and reduce cardiovascular death in adults with type 2 diabetes (T2D), the SGLT-2* inhibitor empagliflozin reduced hospitalization for heart failure (HFH) or cardiovascular death and delayed renal function decline when added to recommended therapy in patients with heart failure and reduced ejection fraction (HFrEF) in the EMPEROR-Reduced** trial. The EMPEROR-Preserved** trial has now shown that the benefits of empagliflozin extend to patients with heart failure and preserved ejection fraction (HFpEF).
Empagliflozin: A new dawn for heart failure treatment across the ejection fraction spectrum
06 Jun 2022
Very low HBsAg levels predict HBsAg loss, disease remission after therapy cessation
Following discontinuation of nucleot(s)ide analogue therapy, only about one-third of patients with HBeAg-negative chronic hepatitis B (CHB) achieve disease remission, with rare HBsAg loss, as reported in a study. The likelihood of HBsAg loss and disease remission is high in the presence of very low HBsAg levels at baseline.
Very low HBsAg levels predict HBsAg loss, disease remission after therapy cessation
04 Jun 2022
Step-down therapy may be the better strategy for certain COPD patients
Switching from triple therapy to dual bronchodilation improves symptom control in patients with chronic obstructive pulmonary disease (COPD) in a new analysis of the DACCORD study.
Step-down therapy may be the better strategy for certain COPD patients
03 Jun 2022
HRT use tied to reduced COVID-19 death risk
The use of hormonal replacement therapy (HRT) among postmenopausal women may be associated with a reduced risk of mortality after a COVID-19 diagnosis, according to a retrospective study from Sweden.