News & Updates

HPV self-sampling with isothermal amplification detection may become part of cervical cancer screening

05 Dec 2023 by

A prospective study in women attending a colposcopy clinic in Hong Kong supports the use of self-sampling with an isothermal amplification (AmpFire)–based assay for human papillomavirus (HPV) detection in cervical cancer screening, showing substantial agreement with clinician sampling using either the AmpFire-based or polymerase chain reaction (PCR)–based reference assay.

HPV self-sampling with isothermal amplification detection may become part of cervical cancer screening

05 Dec 2023

HPV ctDNA testing identifies cervical cancer patients at high risk of relapse after CRT

05 Dec 2023 by

Detection of human papilloma virus (HPV) circulating tumour DNA (ctDNA) after completion of chemoradiation therapy (CRT) is independently associated with inferior progression-free survival (PFS) in patients with cervical cancer, a prospective multicentre study has shown. According to the researchers, early HPV ctDNA testing after CRT can identify patients at high risk of relapse.

HPV ctDNA testing identifies cervical cancer patients at high risk of relapse after CRT

05 Dec 2023

LIBRETTO-431: Selpercatinib as 1L SoC for RET fusion–positive NSCLC

05 Dec 2023 by

Selpercatinib, a selective RET kinase inhibitor, showed superior efficacy vs chemotherapy and pembrolizumab as first-line (1L) treatment in patients with stage IIIB–IV nonsquamous non-small-cell lung cancer (NSCLC) with RET gene fusions, according to results of the open-label phase III LIBRETTO-431 study presented at the European Society for Medical Oncology Congress 2023 (ESMO 2023).

LIBRETTO-431: Selpercatinib as 1L SoC for RET fusion–positive NSCLC

05 Dec 2023

Pertuzumab plus high-dose trastuzumab shows promise for selected patients with HER2-positive MBC

04 Dec 2023

Treatment with pertuzumab plus high-dose trastuzumab appears to confer survival benefits in patients with HER2-positive metastatic breast cancer (MBC) with progressive central nervous system (CNS) metastases following radiotherapy, according to the phase II PATRICIA study.

Pertuzumab plus high-dose trastuzumab shows promise for selected patients with HER2-positive MBC

04 Dec 2023

Immunosuppression does not raise risk of overall, cancer mortality

01 Dec 2023

Use of immunosuppressants does not appear to increase the incidence of all-cause and cancer mortality in patients with noninfectious ocular inflammatory disease (OID) over a median follow-up of 10 years, a recent study has shown.

Immunosuppression does not raise risk of overall, cancer mortality

01 Dec 2023

Intimacy, sexual needs often unmet among partners of terminal cancer patients

01 Dec 2023

There is an unmet need for some hospitalized patients with terminal cancer to have time for intimacy with their partners that requires attention, suggests a study.

Intimacy, sexual needs often unmet among partners of terminal cancer patients

01 Dec 2023

Endoscopic ultrasound-guided CPN effective for abdominal pain in pancreatic cancer

29 Nov 2023

Endoscopic ultrasound-guided celiac plexus neurolysis added to medical management (EUS-CPN+MM) provides beneficial effects for abdominal pain in patients with unresectable pancreatic cancer at 4 and 12 weeks, reports a recent study.

Endoscopic ultrasound-guided CPN effective for abdominal pain in pancreatic cancer

29 Nov 2023

Palliative care in cancer: Which central venous access devices are associated with higher complication rates?

27 Nov 2023 by

A systematic review and meta-analysis by researchers from the University of Hong Kong has shown that the use of peripherally inserted central catheters (PICCs) is associated with a higher rate of complications than central lines in terminally ill cancer patients with central venous access devices (CVADs) for palliative care. No conclusions were reached regarding the use of totally implanted ports (PORTs), as no studies on PORTs were eligible for analysis.

Palliative care in cancer: Which central venous access devices are associated with higher complication rates?

27 Nov 2023

Biweekly cabazitaxel plus G-CSF beneficial to certain older mCRPC patients

27 Nov 2023

In the treatment of older patients with metastatic castration-resistant prostate cancer (mCRPC) who are considered unsuitable candidates for standard cabazitaxel (CBZ) regimens, treatment with CBZ at 16 mg/m2 (biweekly CBZ16) plus prophylactic granulocyte colony–stimulating factor (G-CSF) at each cycle helps reduce the risk of higher grade neutropenia and/or neutropenic complications while yielding similar clinical outcomes, according to the results of the phase III CABASTY trial.

Biweekly cabazitaxel plus G-CSF beneficial to certain older mCRPC patients

27 Nov 2023

Community pharmacists lack readiness to manage oral anticancer medicines

25 Nov 2023

Community pharmacists appear to be lacking in both knowledge and willingness to properly handle the use of oral anticancer medicines (OAMs), according to a Qatar study.

Community pharmacists lack readiness to manage oral anticancer medicines

25 Nov 2023

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HPV self-sampling with isothermal amplification detection may become part of cervical cancer screening

HPV self-sampling with isothermal amplification detection may become part of cervical cancer screening

HPV ctDNA testing identifies cervical cancer patients at high risk of relapse after CRT

HPV ctDNA testing identifies cervical cancer patients at high risk of relapse after CRT

LIBRETTO-431: Selpercatinib as 1L SoC for RET fusion–positive NSCLC

LIBRETTO-431: Selpercatinib as 1L SoC for RET fusion–positive NSCLC

Pertuzumab plus high-dose trastuzumab shows promise for selected patients with HER2-positive MBC

Pertuzumab plus high-dose trastuzumab shows promise for selected patients with HER2-positive MBC

Immunosuppression does not raise risk of overall, cancer mortality

Immunosuppression does not raise risk of overall, cancer mortality

Intimacy, sexual needs often unmet among partners of terminal cancer patients

Intimacy, sexual needs often unmet among partners of terminal cancer patients

Endoscopic ultrasound-guided CPN effective for abdominal pain in pancreatic cancer

Endoscopic ultrasound-guided CPN effective for abdominal pain in pancreatic cancer

Palliative care in cancer: Which central venous access devices are associated with higher complication rates?

Palliative care in cancer: Which central venous access devices are associated with higher complication rates?

Biweekly cabazitaxel plus G-CSF beneficial to certain older mCRPC patients

Biweekly cabazitaxel plus G-CSF beneficial to certain older mCRPC patients

Community pharmacists lack readiness to manage oral anticancer medicines

Community pharmacists lack readiness to manage oral anticancer medicines