Mavacamten improves symptoms in nonobstructive hypertrophic cardiomyopathy
The novel myosin inhibitor mavacamten is well tolerated in patients with symptomatic nonobstructive hypertrophic cardiomyopathy (nHCM) and leads to a significant decrease in N-terminal pro–B-type natriuretic peptide (NT-proBNP) and cardiac troponin I (cTnI), which suggests improvement in myocardial wall stress, a study has shown.