News & Updates

Inclisiran sustains LDL-C reduction in high-risk patients with ASCVD

03 Dec 2021 by

Treatment with inclisiran consistently reduced low-density lipoprotein cholesterol (LDL-C) levels in patients with, or at high risk of, atherosclerotic cardiovascular disease (ASCVD), regardless of glycaemic status, based on a pooled analysis of the ORION-10* and ORION-11** studies presented at AHA 2021.

Inclisiran sustains LDL-C reduction in high-risk patients with ASCVD

03 Dec 2021

Milvexian prevents VTE after knee arthroplasty, bleeding risk low

02 Dec 2021 by

Postoperative treatment with the oral factor XIa inhibitor milvexian could help prevent the incidence of venous thromboembolism (VTE) in patients undergoing elective knee arthroplasty, according to results of a phase II trial presented at AHA 2021.

Milvexian prevents VTE after knee arthroplasty, bleeding risk low

02 Dec 2021

Two-dose hep-B vaccine more seroprotective than three-dose regimen in chronic liver disease patients

02 Dec 2021 by

In a pooled post hoc analysis of three phase III trials, a novel two-dose hepatitis B (hep-B) vaccine regimen trumped the traditional three-dose regimen in inducing seroprotection in patients with chronic liver disease (CLD).

Two-dose hep-B vaccine more seroprotective than three-dose regimen in chronic liver disease patients

02 Dec 2021

Does statin affect performance of PSA screening?

02 Dec 2021 by

Prostate-specific antigen (PSA) screening was associated with similar decrease in incidence of advanced prostate cancer (PCa) among statin users vs nonusers, but less detection of low-grade localized tumours in the former than the latter — indicating that statin does not compromise the benefits of PSA-based screening while also conferring the benefit of less overdiagnosis of low-risk tumours.

Does statin affect performance of PSA screening?

02 Dec 2021

Is docetaxel helpful in metastatic hormone-sensitive prostate cancer?

02 Dec 2021

Treatment with docetaxel appears beneficial in patients with low- and high-burden metastatic hormone-sensitive prostate cancer, a study has shown. However, no consistent differences for overall survival are seen in subgroup analyses as regards volume of metastatic disease.

Is docetaxel helpful in metastatic hormone-sensitive prostate cancer?

02 Dec 2021

Nivolumab a potential treatment for metastatic thymic epithelial tumours

02 Dec 2021

Nivolumab is a promising therapy for patients with thymic epithelial tumours who have received multiple-line treatments, suggests a study. However, the high rate of severe toxicities specifies a need to find out a reliable marker to predict patients who will derive benefit or exhibit toxicity.

Nivolumab a potential treatment for metastatic thymic epithelial tumours

02 Dec 2021

Lefamulin: An alternative to moxifloxacin in pneumonia treatment?

01 Dec 2021 by

The pleuromutilin inhibitor lefamulin shows similarly high efficacy as moxifloxacin (a standard fluoroquinolone therapy for clearing bacterial pneumonia) regardless of whether it was for unilobar or multilobar pneumonia, according to pooled data of the LEAP* 1 and 2 studies.

Lefamulin: An alternative to moxifloxacin in pneumonia treatment?

01 Dec 2021

Fimasartan noninferior to perindopril in older adults with essential hypertension

01 Dec 2021 by

In the treatment of older patients with essential hypertension, fimasartan alone or combined with hydrochlorothiazide demonstrates comparable safety and efficacy to perindopril monotherapy or in combination with indapamide, as shown in the results of a phase IIIb trial.

Fimasartan noninferior to perindopril in older adults with essential hypertension

01 Dec 2021

Initiation of biosimilar pegfilgrastim helps reduce cost, financial pressure on healthcare system

01 Dec 2021

The introduction of pegfilgrastim biosimilar may lower the cost and lessen some of the financial pressure on the healthcare system, suggests a study in France.

Initiation of biosimilar pegfilgrastim helps reduce cost, financial pressure on healthcare system

01 Dec 2021

Folate supplementation helps increase ovarian reserve

01 Dec 2021

Higher intake of folate, specifically from supplements, results in a modest increase in ovarian reserve among women, as shown in a study.

Folate supplementation helps increase ovarian reserve

01 Dec 2021

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Inclisiran sustains LDL-C reduction in high-risk patients with ASCVD

Inclisiran sustains LDL-C reduction in high-risk patients with ASCVD

Milvexian prevents VTE after knee arthroplasty, bleeding risk low

Milvexian prevents VTE after knee arthroplasty, bleeding risk low

Two-dose hep-B vaccine more seroprotective than three-dose regimen in chronic liver disease patients

Two-dose hep-B vaccine more seroprotective than three-dose regimen in chronic liver disease patients

Does statin affect performance of PSA screening?

Does statin affect performance of PSA screening?

Is docetaxel helpful in metastatic hormone-sensitive prostate cancer?

Is docetaxel helpful in metastatic hormone-sensitive prostate cancer?

Nivolumab a potential treatment for metastatic thymic epithelial tumours

Nivolumab a potential treatment for metastatic thymic epithelial tumours

Lefamulin: An alternative to moxifloxacin in pneumonia treatment?

Lefamulin: An alternative to moxifloxacin in pneumonia treatment?

Fimasartan noninferior to perindopril in older adults with essential hypertension

Fimasartan noninferior to perindopril in older adults with essential hypertension

Initiation of biosimilar pegfilgrastim helps reduce cost, financial pressure on healthcare system

Initiation of biosimilar pegfilgrastim helps reduce cost, financial pressure on healthcare system

Folate supplementation helps increase ovarian reserve

Folate supplementation helps increase ovarian reserve