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Local plus systemic therapies improve survival in HCC
Combination therapy using yttrium 90 (Y90) radioembolization and sorafenib/nivolumab for patients with hepatocellular carcinoma (HCC), with hepatic vein (HV) or inferior vena cava (IVC) invasion, results in better outcomes, as indicated by increased response rates, overall survival (OS), and progression-free survival (PFS) benefits, a study has found.
Local plus systemic therapies improve survival in HCC
07 Mar 2023Lower torso exercise plus respiratory training beneficial in asthma
Breathing exercise devices such as a conventional threshold loading training (TLT) device or an innovative respiratory training (IRT) device, when used in combination with lower torso sports training (LTST), proved beneficial in improving pulmonary function, exercise capacity, and quality of life (QoL) in individuals with asthma, a study suggests. However, IRT trumped TLT in terms of improvements in some respiratory and physical performance variables.
Lower torso exercise plus respiratory training beneficial in asthma
07 Mar 2023Darolutamide-containing triplet regimen ups survival in mHSPC regardless of disease volume, risk
In a post hoc analysis of the phase III ARASENS study, the triplet regimen comprising darolutamide, androgen deprivation therapy (ADT), and docetaxel continued to show overall survival (OS) benefit for metastatic hormone-sensitive prostate cancer (mHSPC) irrespective of disease volume and risk.
Darolutamide-containing triplet regimen ups survival in mHSPC regardless of disease volume, risk
06 Mar 2023Mesalamine shows modest benefit in IBS
Treatment with mesalamine may only have modest efficacy for the global symptoms of irritable bowel syndrome (IBS), specifically IBS that causes increased diarrhoea, according to the results of a meta-analysis. However, the quality of evidence appears to be low.