News & Updates

HbA1c variability linked to serious infections

16 May 2024

Fluctuations in HbA1c levels in between clinic visits may put individuals with type 2 diabetes (T2D) at increased risk of serious infections, according to a study.

HbA1c variability linked to serious infections

16 May 2024

Sequential fosfomycin therapy beneficial in bacterial prostatitis caused by multidrug-resistant E coli

14 May 2024 by

Sequential treatment with the oral antibiotic fosfomycin appears to be safe and effective in the management of patients with acute bacterial prostatitis secondary to multidrug-resistant Escherichia coli, according to the phase IV FOS-PROST study.

Sequential fosfomycin therapy beneficial in bacterial prostatitis caused by multidrug-resistant E coli

14 May 2024

Positive antibiotic interactions for MRSA bacteraemia tied to lower 14-day mortality

14 May 2024 by

Patients with positive in-vitro antibiotic interactions with vancomycin or daptomycin plus an antistaphylococcal β-lactam for methicillin-resistant Staphylococcus aureus (MRSA) bacteraemia appear to have greater survival at 2 weeks, as shown in a post hoc analysis of the CAMERA-2* study.

Positive antibiotic interactions for MRSA bacteraemia tied to lower 14-day mortality

14 May 2024

Inappropriate pneumonia diagnosis common, potentially harmful for hospitalized older adults

14 May 2024

The frequency of inappropriate diagnosis of community acquired pneumonia (CAP) is relatively high among hospitalized adults, especially those who are older, have dementia, or present with altered mental status, according to a study. In such cases, a full-course antibiotic treatment may be detrimental.

Inappropriate pneumonia diagnosis common, potentially harmful for hospitalized older adults

14 May 2024

RSV vaccine plus flu or COVID-19 shots safe, feasible in older adults

13 May 2024 by

Coadministration of mRNA-1345, a respiratory syncytial virus (RSV) vaccine, with an influenza (flu) or a COVID-19 vaccine in older adults exhibits good tolerability and has an acceptable reactogenicity profile, according to a US study presented at ESCMID Global Congress 2024.

RSV vaccine plus flu or COVID-19 shots safe, feasible in older adults

13 May 2024

Ceftobiprole as good as daptomycin in achieving S. aureus bloodstream clearance

13 May 2024 by

Ceftobiprole was as effective as daptomycin in achieving bloodstream clearance in patients with complicated Staphylococcus aureus (S. aureus) bacteremia, according to the ERADICATE study presented at ESCMID 2024.

Ceftobiprole as good as daptomycin in achieving S. aureus bloodstream clearance

13 May 2024

Aztreonam-avibactam cracks into hard-to-treat MBL-producing MDR-GNB

13 May 2024 by

The fixed-dose combination of aztreonam and avibactam yields a 41.7-percent clinical cure rate in serious infections caused by metallo-β-lactamase (MBL)–producing multidrug-resistant (MDR) Gram-negative bacteria (GNB), according to the results from the phase III ASSEMBLE trial.

Aztreonam-avibactam cracks into hard-to-treat MBL-producing MDR-GNB

13 May 2024

First-in-class oral antibiotic for uncomplicated urogenital gonorrhea clears phase III study

11 May 2024 by

The first-in-class oral bacterial topoisomerase inhibitor zoliflodacin has demonstrated noninferior efficacy versus a combination of ceftriaxone plus azithromycin in the treatment of uncomplicated urogenital gonorrhoea, with favourable safety and tolerability profile.

First-in-class oral antibiotic for uncomplicated urogenital gonorrhea clears phase III study

11 May 2024

Zoliflodacin noninferior to dual therapy for uncomplicated urogenital gonorrhoea

11 May 2024 by

Zoliflodacin was noninferior to ceftriaxone plus azithromycin in achieving microbiological cure at the urogenital site in patients with uncomplicated gonorrhoea, according to a study presented at ESCMID 2024.

Zoliflodacin noninferior to dual therapy for uncomplicated urogenital gonorrhoea

11 May 2024

Dequalinium chloride works as well as metronidazole for bacterial vaginosis

10 May 2024 by

In the treatment of bacterial vaginosis, dequalinium chloride is noninferior to metronidazole, with similarly high cure rates but better tolerability and fewer adverse events, according to a phase IV study.

Dequalinium chloride works as well as metronidazole for bacterial vaginosis

10 May 2024

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HbA1c variability linked to serious infections

HbA1c variability linked to serious infections

Sequential fosfomycin therapy beneficial in bacterial prostatitis caused by multidrug-resistant E coli

Sequential fosfomycin therapy beneficial in bacterial prostatitis caused by multidrug-resistant E coli

Positive antibiotic interactions for MRSA bacteraemia tied to lower 14-day mortality

Positive antibiotic interactions for MRSA bacteraemia tied to lower 14-day mortality

Inappropriate pneumonia diagnosis common, potentially harmful for hospitalized older adults

Inappropriate pneumonia diagnosis common, potentially harmful for hospitalized older adults

RSV vaccine plus flu or COVID-19 shots safe, feasible in older adults

RSV vaccine plus flu or COVID-19 shots safe, feasible in older adults

Ceftobiprole as good as daptomycin in achieving S. aureus bloodstream clearance

Ceftobiprole as good as daptomycin in achieving S. aureus bloodstream clearance

Aztreonam-avibactam cracks into hard-to-treat MBL-producing MDR-GNB

Aztreonam-avibactam cracks into hard-to-treat MBL-producing MDR-GNB

First-in-class oral antibiotic for uncomplicated urogenital gonorrhea clears phase III study

First-in-class oral antibiotic for uncomplicated urogenital gonorrhea clears phase III study

Zoliflodacin noninferior to dual therapy for uncomplicated urogenital gonorrhoea

Zoliflodacin noninferior to dual therapy for uncomplicated urogenital gonorrhoea

Dequalinium chloride works as well as metronidazole for bacterial vaginosis

Dequalinium chloride works as well as metronidazole for bacterial vaginosis