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There is no clear evidence that gout and hyperuricaemia contribute to a heightened risk of dementia, although both conditions may be protective against Alzheimer’s disease, as shown in a study.
The increasing use of social media and online reviews has made it easier for patients to comment publicly—on Facebook and Google reviews, for instance—on the care they receive. Positive comments are heartening for any healthcare professional to read.
The oral Janus kinase inhibitor upadacitinib – which has gained approval for the treatment of rheumatoid arthritis (RA) – showed potential for treating individuals with psoriatic arthritis (PsA) who have insufficient response to nonbiologic disease-modifying antirheumatic drugs, according to the phase III SELECT-PsA 1 trial.
Patients with axial spondyloarthritis (AxSpA) have decreased exercise capacity, with low heart rate recovery tied to elevated 10-year risk of cardiovascular (CV) events, as reported in a study.
The use of apremilast consistently reduced the number and pain due to oral ulcers in both men and women with active Behçet’s syndrome, according to a subgroup analysis of the RELIEF* study presented at EULAR 2021.
Analysis of the German COVID-19 registry suggests that patients with rheumatic or musculoskeletal diseases (RMDs) who are treated with tumour necrosis factor (TNF) inhibitors appear to be at lower risk of severe outcomes of COVID-19 compared with those treated with other (non-TNF inhibitor) immunomodulatory treatments (OIDs).
Aquatic-based plyometric exercises are safe and improve muscle strength, fatigue, and functional ability in patients with juvenile dermatomyositis, as shown in a study.
Certain therapies used for rheumatic diseases, including rituximab, are associated with worse outcomes for COVID-19 and reduced immune response after COVID-19 vaccination in patients with rheumatic diseases, according to two studies presented at the virtual EULAR 2021 Congress.
Treatment with the fully human anti-IL17 monoclonal antibody secukinumab resulted in fewer, and a longer time to, disease flares in children and adolescents with enthesitis-related arthritis (ERA) and juvenile psoriatic arthritis (JPsA), results of the phase III JUNIPERA trial showed.
Eligible patients with rheumatic diseases (PRDs) are strongly urged to get vaccinated against COVID-19, and the vaccine may be administered while on immunomodulatory therapy, preferably during an inactive disease state, and without requiring testing for postvaccination antibody titres, according to recommendations from the Singapore Chapter of Rheumatologists.
