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Maintenance olaparib rechallenge improves PFS in ovarian cancer patients
Restarting treatment with maintenance olaparib in ovarian cancer patients who had received one prior poly(ADP-ribose) polymerase (PARP) inhibitor and at least two lines of platinum-based chemotherapy results in a modest but significant improvement in progression-free survival (PFS) compared with placebo, results of a phase III study have shown.
Maintenance olaparib rechallenge improves PFS in ovarian cancer patients
13 Jan 2024Semaglutide trims down weight in patients with severe obesity
Use of semaglutide 2.4 mg results in substantial weight reduction in patients with severe obesity who had previously undergone bariatric surgery (BS) but failed to achieve satisfactory weight loss, reports a recent study.
Semaglutide trims down weight in patients with severe obesity
12 Jan 2024Linezolid flops against benzathine penicillin G for early syphilis
In the treatment of patients with early syphilis, a 5-day course of linezolid does not appear to perform as well as the standard of care benzathine penicillin G (BPG), as shown in a study.
Linezolid flops against benzathine penicillin G for early syphilis
12 Jan 2024Add-on carfilzomib yields benefits in transplant-ineligible NDMM patients
The addition of carfilzomib to lenalidomide and dexamethasone (KRd) improved outcomes in individuals with newly diagnosed fit or intermediate-fit multiple myeloma who are transplant ineligible (NTE NDMM) as opposed to Rd only in the phase III EMN20 trial.