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Baricitinib, ivermectin, favipiravir rank high among COVID-19 oral antivirals
Baricitinib, ivermectin, and favipiravir stood out in terms of efficacy in a network meta-analysis evaluating various novel oral antivirals for the treatment of COVID-19.
Baricitinib, ivermectin, favipiravir rank high among COVID-19 oral antivirals
15 Dec 2023MAGNITUDE updates in Asian cohort boost NIRA-AAP benefit in BRCA+ mCRPC
In the second interim analysis of the Asian cohort from the phase III MAGNITUDE study, a combination regimen comprising niraparib and abiraterone acetate plus prednisone (NIRA-AAP) improved clinical outcomes in patients with BRCA+ metastatic castration-resistant prostate cancer (mCRPC).
MAGNITUDE updates in Asian cohort boost NIRA-AAP benefit in BRCA+ mCRPC
13 Dec 2023BPaLM regimen continues to show benefit against rifampicin-resistant tuberculosis
In the treatment of patients with rifampicin-resistant tuberculosis, a 6-month oral regimen consisting of bedaquiline, pretomanid, linezolid, and moxifloxacin (BPaLM) is safe and efficacious and compares favourably with standard of care, as shown in the final data from the phase IIB-III TB-PRACTECAL study.
BPaLM regimen continues to show benefit against rifampicin-resistant tuberculosis
12 Dec 2023Molecular-based guided therapy shows promise in treatment-resistant HCC/H-CCK
A recent study has demonstrated the feasibility of molecular-based targeted therapy in patients with hepatocellular carcinoma (HCC)/hepato-cholangiocarcinoma (H-CCK) that progressed while under treatment with atezolizumab/bevacizumab.