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Two-drug dolutegravir-based regimen a valid alternative for pregnant women with HIV
For pregnant women with HIV who are receiving dolutegravir (DTG)-based therapies, the two-drug regimen works just as well as three-drug regimens at keeping the viral load to "undetectable" levels without exerting serious adverse effects on neonatal outcomes, according to a study presented at HIV Glasgow 2022 Congress.
Two-drug dolutegravir-based regimen a valid alternative for pregnant women with HIV
07 Nov 2022Switch to B/F/TAF sustains virologic suppression in adult PLHIV
Adult people with HIV-1 (PLHIV) who switched to bictegravir/emtricitabine/tenofovir alafenamide (B/F/TAF) after initially taking dolutegravir/abacavir/lamivudine (DTG/ABC/3TC) or DTG+F/TAF show a consistently high virologic suppression and have few discontinuations over 5 years of follow-up, according to a study presented at the HIV Glasgow 2022 Congress.
Switch to B/F/TAF sustains virologic suppression in adult PLHIV
07 Nov 2022Statin use linked to reduced risk of severe COVID-19 outcomes
Patients who are on long-term statin therapy may have a reduced risk of severe COVID-19–related outcomes including mortality, intensive care unit (ICU) admission, and requirement for mechanical ventilation, according to a study presented at Anesthesiology 2022.
Statin use linked to reduced risk of severe COVID-19 outcomes
06 Nov 2022Third-dose vaccine beats tolerance in cirrhotic COVID-19 patients
A third-dose administration of a COVID-19 mRNA vaccine results in a more substantial decrease in COVID-19 in patients with cirrhosis compared with the general population, according to a study. This suggests that the third dose can overcome vaccine hyporesponsiveness in this population.
Third-dose vaccine beats tolerance in cirrhotic COVID-19 patients
06 Nov 2022Once-a-day pill as switch option receives thumbs up across multiple HIV populations
Switching to the once-a-day, fixed-dose pill that contains bictegravir, emtricitabine, and tenofovir (BIC/FTC/TAF) appears to be safe and effective in older HIV patients and in people living with HIV (PLHIV) with pretreatment or treatment-acquired resistance, in addition to yielding metabolic benefits, according to studies presented at HIV Glasgow 2022.
Once-a-day pill as switch option receives thumbs up across multiple HIV populations
04 Nov 2022Detectable viral loads persist in one-third of PLHIV in Asia-Pacific region
Between 2015 and 2020, nearly a third of people living with HIV (PLHIV) in Asia-Pacific countries still show a detectable viral load, according to a study presented at the HIV Glasgow 2022 Congress.
Detectable viral loads persist in one-third of PLHIV in Asia-Pacific region
04 Nov 2022Vebicorvir plus entecavir safe, effective in chronic HBV patients
The addition of vebicorvir to entecavir in treatment-naïve patients with chronic hepatitis B virus (HBV) infection provides further antiviral activity, with a positive safety and tolerability profile, results of a phase II trial have shown.