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Concomitant insulin may counter renoprotective effects of SGLT2is in T2D patients with CKD
Renal composite outcomes (RCO) appear to be less favourable among type 2 diabetes (T2D) patients with chronic kidney disease (CKD) treated with insulin and sodium-glucose cotransporter 2 inhibitors (SGLT2i), a recent Japan study has found.
Concomitant insulin may counter renoprotective effects of SGLT2is in T2D patients with CKD
16 Jun 2022
Fixed-dose albuterol/budesonide an effective rescue med in moderate-to-severe asthma
A fixed-dose combination of albuterol and budesonide, delivered as needed, reduced the risk of severe exacerbations in patients with moderate-to-severe asthma inadequately controlled with corticosteroid maintenance therapy, according to results of the phase III MANDALA trial presented at ATS 2022.
Fixed-dose albuterol/budesonide an effective rescue med in moderate-to-severe asthma
15 Jun 2022
Is SGLT-2 inhibitor better than metformin as first-line T2D treatment?
Use of sodium–glucose cotransporter-2 inhibitors (SGLT-2i) as first-line treatment for type 2 diabetes (T2D) delivers a comparable risk for myocardial infarction (MI), stroke, and mortality; a lower risk for hospitalization for heart failure (HHF)/mortality and HHF; and a similar safety profile, except for a higher risk for genital infections, when compared to treatment with metformin, a study has found.
Is SGLT-2 inhibitor better than metformin as first-line T2D treatment?
15 Jun 2022
Familiarity with EuroLupus dosing for cSLE remains low despite uptick in use
Paediatric specialists now use low-dose EuroLupus cyclophosphamide (CYC) more than they did a decade ago in the treatment of childhood-onset systemic lupus erythematosus (cSLE), reports a study in North America. However, familiarity with EuroLupus dosing is still low.
