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Overweight, obesity up risk of urinary incontinence
Chronic, increased body mass index (BMI) may lead to an increased risk of urinary incontinence (UI) later in life, according to a study of postmenopausal women. In addition, symptom severity may get worse with the duration of increased BMI status.
Overweight, obesity up risk of urinary incontinence
11 May 2022
Foetal risk low in LMWH-exposed women during pregnancy
Pregnant women with preconception venous thromboembolism (VTE) who have no exposure to any anticoagulant and those on low-molecular-weight heparin (LMWH) have the lowest risk of foetal adverse outcomes, reveals a study, which supports the recommendation of LMWH during pregnancy.
Foetal risk low in LMWH-exposed women during pregnancy
11 May 2022
Sotorasib demonstrates durable efficacy in KRASG12C-mutated NSCLC
The KRASG12C inhibitor sotorasib has demonstrated durable efficacy in patients with locally advanced or metastatic KRASG12C-mutated non-small-cell lung cancer (NSCLC), with 2-year overall survival (OS) reported in one-third of patients in the CodeBreaK 100 trial.
Sotorasib demonstrates durable efficacy in KRASG12C-mutated NSCLC
11 May 2022
Adding canakinumab to SoC confers no survival benefit in advanced NSCLC
The addition of the monoclonal anti-interleukin-1β antibody canakinumab to the standard of care (SoC) regimen of platinum doublet chemotherapy and pembrolizumab in the first-line setting did not improve progression-free survival (PFS) or overall survival (OS) in patients with advanced non-small-cell lung cancer (NSCLC), results of the phase III CANOPY-1 trial showed.
Adding canakinumab to SoC confers no survival benefit in advanced NSCLC
10 May 2022
Musculoskeletal pain common in T2D but does not influence treatment goals
Musculoskeletal pain is a common coexisting symptom in patients with type 2 diabetes (T2D), with most patients having knee or lower back pain, a study reports. However, despite the major disability burden associated with these types of pain, it does not seem to get in the way of achieving treatment targets.
