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![Accelerated cognitive decline risk with diabetes higher in women than men](https://sitmspst.blob.core.windows.net/images/articles/mild-cognitive-impairment-accompanied-by-disability-mental-disorder-226bb343-67a4-407a-9dd9-477370101907-square.jpg)
Accelerated cognitive decline risk with diabetes higher in women than men
Among patients with type 2 diabetes (T2D), women appear to be at greater risk of accelerated cognitive decline than men, as reported in a study. This risk increase can be partly explained by depressive symptoms being greater among women.
Accelerated cognitive decline risk with diabetes higher in women than men
01 Nov 2021![Pembrolizumab extends RFS in stage II melanoma](https://sitmspst.blob.core.windows.net/images/articles/pembrolizumab-extends-rfs-in-stage-ii-melanoma-661aff51-bfa0-46e8-82c9-c25c10f1983e-square.jpg)
Pembrolizumab extends RFS in stage II melanoma
Pembrolizumab extended recurrence-free survival (RFS) in patients with high-risk stage II melanoma who had undergone complete resection, interim analysis results of the phase III KEYNOTE-716 trial showed.
Pembrolizumab extends RFS in stage II melanoma
01 Nov 2021![Rapid test for COVID-19 not so perfect](https://sitmspst.blob.core.windows.net/images/articles/rapid-test-for-covid-19-not-so-perfect-a1996879-dd0b-4f6e-82d3-3c047d606881-square.jpg)
Rapid test for COVID-19 not so perfect
Panbio, a rapid antigen test for SARS-CoV-2, has good specificity but limited sensitivity, as shown in a study. As such, all negative tests have to be confirmed with RT-PCR, especially in the presence of related symptoms, in settings with high community infection rate, and in cases of direct contact with confirmed COVID-19 patients.
Rapid test for COVID-19 not so perfect
01 Nov 2021![Mirtazapine of no benefit for agitated behaviours in dementia](https://sitmspst.blob.core.windows.net/images/articles/ag-demen-2b016e6a-f410-4aeb-b4db-3a808f46dc6f-square.jpg)
Mirtazapine of no benefit for agitated behaviours in dementia
Results of a randomized, double-blind, placebo-controlled trial show no benefit with mirtazapine, given with normal clinical care, for treatment of clinically significant agitation in patients with dementia compared with placebo, with a potentially higher mortality observed with the use of mirtazapine.
Mirtazapine of no benefit for agitated behaviours in dementia
01 Nov 2021![Noninvasive tests predict liver-related events in early alcohol-related liver disease](https://sitmspst.blob.core.windows.net/images/articles/alcoholic-hepatitis-ce77fd49-7ccc-4f1b-b3e3-f89685f322f7-square.jpg)
Noninvasive tests predict liver-related events in early alcohol-related liver disease
In patients with early-stage alcohol-related liver disease, transient elastography (TE), the enhanced liver fibrosis test (ELF), and 2-dimensional shear-wave elastography (2D-SWE) can reliably predict the risk of symptomatic liver events, a recent study has found.
Noninvasive tests predict liver-related events in early alcohol-related liver disease
01 Nov 2021![Sustained benefit with anti-TNFα less likely to lead to subsequent loss of response in IBD](https://sitmspst.blob.core.windows.net/images/articles/crohnibd-c59f3551-20a3-4b0c-805a-5627aaaec3fd-square.jpg)
Sustained benefit with anti-TNFα less likely to lead to subsequent loss of response in IBD
Inflammatory bowel disease (IBD) patients receiving treatment with antitumour necrosis factor alpha (anti-TNFα) for more than 2 years represent a distinct group who obtain prolonged clinical benefit and tolerate maintenance treatment, according to a study.