News &amp; Updates

The risk of stroke increases with growing difference between resting and maximal exercise systolic blood pressure (SBP), independent of BP at rest, according to a study. This suggests that an exaggerated BP response to physical exercise is independently predictive of stroke.

Exaggerated BP response to exercise predicts stroke

Lung function more stable but death risk higher in advanced IPF patients on antifibrotics

Patients with advanced idiopathic pulmonary fibrosis (IPF) at the time of initiation with nintedanib or pirfenidone demonstrate more stable lung function over time, but substantially higher risk of death, compared to those with mild-to-moderate IPF, according to the results of a recent study.

Lung function more stable but death risk higher in advanced IPF patients on antifibrotics

Lazy eye common in poor, obese teens

A new study linked amblyopia – otherwise called lazy eye – to poverty, below-average cognitive scores, and yes, obesity, in teenagers.

Lazy eye common in poor, obese teens

Abnormal STE myocardial function prevalent in women with HELLP syndrome history

The rate of abnormal speckle-tracking echocardiography (STE) myocardial function is high during the first years following a pregnancy complicated by haemolysis, elevated liver enzymes, and low platelets (HELLP) syndrome, regardless of whether there was concomitant pre-eclampsia (PE), reveals a study.

Abnormal STE myocardial function prevalent in women with HELLP syndrome history

Olanzapine a favourable alternative to dexamethasone for CINV

Olanzapine administered at a dose of 5 mg was noninferior to dexamethasone and is associated with fewer adverse effects than dexamethasone for chemotherapy-induced nausea and vomiting (CINV), according to data presented at ESMO 2021.

Olanzapine a favourable alternative to dexamethasone for CINV

27 Sep 2021

Smartphone app helps improve physical function in peripheral artery disease

TrackPAD, a mobile phone health app designed specifically for patients with peripheral artery disease (PAD), leads to better exercise outcomes, improving their 6-minute walking distance (6MWD) and disease-related quality of life (QoL), according to a recent study.

Smartphone app helps improve physical function in peripheral artery disease

Ribociclib plus letrozole improves OS in hormone receptor–positive, HER2-negative advanced breast cancer

A combined regimen of ribociclib plus letrozole as first-line treatment provides a statistically significant and clinically meaningful overall survival (OS) benefit vs placebo plus letrozole in postmenopausal patients with hormone receptor–positive and HER2-negative advanced breast cancer (BC), results of the phase III MONALEESA-2 study have shown.

Ribociclib plus letrozole improves OS in hormone receptor–positive, HER2-negative advanced breast cancer

27 Sep 2021

Further data back COVID booster shot in transplant patients

26 Sep 2021 by

Antibody response was significantly enhanced with a third dose of mRNA-1273 vaccine in organ transplant recipients, reveal data of a randomized trial.

Further data back COVID booster shot in transplant patients

Aggressive hydration averts contrast-induced AKI in STEMI patients undergoing PCI

Perioperative aggressive hydration appears to be better than general hydration at preventing contrast-induced acute kidney injury (AKI) among patients with myocardial infarction with ST-segment elevation (STEMI) undergoing primary percutaneous coronary intervention (PCI), a study has found.

Aggressive hydration averts contrast-induced AKI in STEMI patients undergoing PCI

26 Sep 2021

Long-term risk of anticoagulant-related bleeding high in patients with first unprovoked VTE

There appears to be substantial long-term risks and consequences of anticoagulant-related major bleeding in patients with a first unprovoked venous thromboembolism (VTE), suggests a recent study.

Long-term risk of anticoagulant-related bleeding high in patients with first unprovoked VTE