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Pembrolizumab looks good for treated, advanced MSI-H/dMMR endometrial cancer
Use of pembrolizumab helps maintain or improve health-related quality of life in patients with previously treated, advanced endometrial cancer characterized by high levels of microsatellite instability (MSI) or deficient mismatch repair (MSI-H/dMMR), according to data from the phase II KEYNOTE-158 study.
Pembrolizumab looks good for treated, advanced MSI-H/dMMR endometrial cancer
18 Jul 2022Is laparoscopic better than open partial nephrectomy for renal tumours?
Patients with renal tumours who have undergone laparoscopic partial nephrectomy (LPN) have shown similar surgical and oncologic outcomes as those treated with open partial nephrectomy (OPN), reports a study.
Is laparoscopic better than open partial nephrectomy for renal tumours?
17 Jul 2022Mood, anxiety disorders may prolong hospital stay following radical cystectomy
For bladder cancer patients scheduled to undergo radical cystectomy, the presence of mood and/or anxiety disorders may lead to a longer length of hospital stay and increase the likelihood of discharge to a nonhome facility, a study reports.
Mood, anxiety disorders may prolong hospital stay following radical cystectomy
16 Jul 2022Cetuximab plus chemoradiotherapy feasible in women with cervical carcinoma
Treatment with cetuximab plus cisplatin 30 mg/m2 and radiotherapy appears safe and well tolerated in women with cervical carcinoma, a study has shown. In addition, fluorine-18 fluorodeoxyglucose-positron emission tomography/computed tomography (18F-FDG-PET/CT) has exhibited early evidence of response to neoadjuvant cetuximab.
Cetuximab plus chemoradiotherapy feasible in women with cervical carcinoma
16 Jul 2022Upfront ASCT + RVd improves PFS in NDMM
Upfront autologous stem cell transplantation (ASCT) plus lenalidomide, bortezomib, and dexamethasone (RVd) significantly improves progression-free survival (PFS) in patients with newly diagnosed multiple myeloma (NDMM), results of the phase III DETERMINATION trial showed.
Upfront ASCT + RVd improves PFS in NDMM
16 Jul 2022Family history plus obesity/hyperglycaemia redoubles renal cell cancer risk
The interaction between genetic and environmental factors, specifically obesity and hyperglycaemia, contributes to an increased risk of renal cell cancer (RCC), suggests a study.
Family history plus obesity/hyperglycaemia redoubles renal cell cancer risk
16 Jul 2022Nonoperative management safe, feasible after complete response in rectal cancer
Patients with locally advanced rectal cancer who achieve complete response (CR) following sequential short-course radiation therapy (SCRT) and chemotherapy appear to benefit from nonoperative management (NOM) with a watch-and-wait strategy, which presents evidence for good anorectal functions, results of a study have shown.