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New models predict skeletal muscle mass reduction with calorie restriction
A recent study has shown that healthy men and women with overweight or obesity who undergo voluntary calorie restriction (CR), without a structure exercise program, attain decreases in skeletal muscle (SM) mass of approximately 2 to 2.5 kg and 1 to 1.5 kg per 10-kg weight loss, respectively.
New models predict skeletal muscle mass reduction with calorie restriction
11 Jan 2024NIH study: Semaglutide associated with lower risk of suicidal ideation
Semaglutide is associated with a 49─73 percent lower risk of suicidal ideation vs other agents for treatment of obesity and type 2 diabetes mellitus (T2DM), a National Institutes of Health (NIH)─funded study has shown.
NIH study: Semaglutide associated with lower risk of suicidal ideation
11 Jan 2024Forgoing radiotherapy possible for select postmenopausal women with early breast cancer
For postmenopausal women with genomically defined low-risk stage I breast cancer who have been initiated on endocrine therapy immediately after breast-conserving surgery, the risk of recurrence is low despite the omission of radiation therapy, as shown in the IDEA* trial.
Forgoing radiotherapy possible for select postmenopausal women with early breast cancer
10 Jan 2024Add-on carfilzomib yields benefits in transplant-ineligible NDMM patients
The addition of carfilzomib to lenalidomide and dexamethasone (KRd) improved outcomes in individuals with newly diagnosed fit or intermediate-fit multiple myeloma who are transplant ineligible (NTE NDMM) as opposed to Rd only in the phase III EMN20 trial.