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Triple therapy with ursodeoxycholic acid, obeticholic acid, and fibrates leads to normalization of biochemical liver tests and pruritus improvement in patients with difficult‐to‐treat primary biliary cholangitis, as shown in a study.
Kidney transplant recipients with low serum bilirubin levels are at greater risk of adverse outcomes, such as graft loss, graft failure, and all-cause mortality, a recent study has found.
In the treatment of patients with gram-positive hospital-acquired or ventilator-associated bacterial pneumonia, tedizolid works as well as linezolid in terms of 28-day all-cause mortality but not investigator-assessed clinical response, according to the results of a phase III trial.
Use of hydroxychloroquine (HCQ) is inversely associated with the risk of cardiovascular events in patients with lupus erythematosus (LE), as indicated by the results of a recent study.
Pelvic and acetabular fractures (PAFs), high-energy injuries that have significant morbidity and mortality, mostly affect young working males, according to a Singapore study. A significant decrease in PAF incidence has also been observed compared to previously published local data.
Primary analysis of the D8110C00001 trial showed that the COVID-19 vaccine AZD1222 had 76 percent efficacy at preventing symptomatic COVID-19.
Induction therapy with alemtuzumab shows outcomes comparable to basiliximab in elderly kidney transplant (KT) recipients, a study has shown.
Use of hormone replacement therapy in menopausal women appears to contribute to an increased risk of developing asthma, a study has found.
In patients with diffuse large B cell lymphoma (DLBCL), hypomagnesemia is associated with worse outcomes after autologous haematopoietic stem cell transplant (AHSCT), a recent study has found.
Patients hospitalized with COVID-19 fare worse when they also have hyperglycaemia on admission, regardless of diabetes status — indicating that hyperglycaemia is a better predictor of severe outcomes from COVID-19 than diabetes, according to a study presented at the 2021 ENDO Meeting.
