News & Updates

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CheckMate 274: Adjuvant nivolumab ups DFS in high-risk bladder cancer

CheckMate 274: Adjuvant nivolumab ups DFS in high-risk bladder cancer

Treatment with the PD-1 immune checkpoint inhibitor nivolumab after radical surgery significantly extends disease-free survival (DFS) compared with placebo in patients with muscle-invasive urothelial carcinoma (MIUC) at high risk of recurrence, regardless of their PD-L1 status, according to the CheckMate 274 study presented at the 2021 ASCO GUCS.

CheckMate 274: Adjuvant nivolumab ups DFS in high-risk bladder cancer

Breastfeeding prevents Asian moms with GDM from becoming lifelong diabetics

Breastfeeding prevents Asian moms with GDM from becoming lifelong diabetics

Breastfeeding has benefits that extend beyond the babies’ health, with a recent study showing that mothers who nurse for at least 6 months are better protected against long-term dysglycaemia, particularly those with a history of gestational diabetes mellitus (GDM), in an Asian setting.

Breastfeeding prevents Asian moms with GDM from becoming lifelong diabetics

Three dietary fat sources show similar impact on liver fat concentration

Three dietary fat sources show similar impact on liver fat concentration

Palm olein, cocoa butter, and soybean oil demonstrated comparable effects on liver fat concentration and amounts of adipose tissue in healthy adults when consumed as part of eucaloric typical Australian diets, according to a study. Moreover, the effects on serum lipids are inconsistent across lipid profiles.

Three dietary fat sources show similar impact on liver fat concentration

Exercise intervention speeds up recovery of frail older adults after acute MI

Exercise intervention speeds up recovery of frail older adults after acute MI

Older adult patients participating in a physical programme exhibit improvement in frailty status at 3 months, but such benefit is attenuated following a shift to a home-based programme, according to a study. Recruitment and retention to this intervention has also been challenging.

Exercise intervention speeds up recovery of frail older adults after acute MI

Patients with achalasia at risk of oesophageal cancer

Patients with achalasia at risk of oesophageal cancer

Achalasia is associated with an increased risk of developing both squamous cell carcinoma and adenocarcinoma of the oesophagus, reveals a study, noting, however, that the annual incidence of oesophageal cancer is rather low.

Patients with achalasia at risk of oesophageal cancer

Nivolumab+cabozantinib demonstrates durable efficacy for renal cancer

Nivolumab+cabozantinib demonstrates durable efficacy for renal cancer

In the extended follow-up of the phase III CheckMate 9ER trial, nivolumab + cabozantinib (NIVO+CABO) continued to fare better than sunitinib for the treatment of advanced renal cell carcinoma (aRCC), regardless of sarcomatoid (sRCC) status.

Nivolumab+cabozantinib demonstrates durable efficacy for renal cancer

Genomics uncovers diverse biological backgrounds of eating disorders

Genomics uncovers diverse biological backgrounds of eating disorders

While major eating disorders share common genetic psychiatric risk, the genetics of body weight regulation may predispose a person to develop a particular eating disorder over others, according to a new study.

Genomics uncovers diverse biological backgrounds of eating disorders

Pregnancy smoking ups retinopathy of prematurity risk

Pregnancy smoking ups retinopathy of prematurity risk

Very preterm infants born to mothers who smoked during pregnancy are at a heightened risk of retinopathy of prematurity (ROP), a recent study has found.

Pregnancy smoking ups retinopathy of prematurity risk

Artesunate drip shows therapeutic benefit in severe malaria

Artesunate drip shows therapeutic benefit in severe malaria

Patients with severe imported malaria appear to fare well with intravenous artesunate, despite an increased incidence of mild-to-moderate post-treatment delayed haemolysis, as reported in a study.

Artesunate drip shows therapeutic benefit in severe malaria

Pregnancy risk factors predict future cerebrovascular disease risk in offspring

Pregnancy risk factors predict future cerebrovascular disease risk in offspring

Disturbances in maternal and foetal growth during pregnancy may spell trouble for the offspring, as they contribute to a heightened risk of developing cerebrovascular diseases in adulthood, a study has found.

Pregnancy risk factors predict future cerebrovascular disease risk in offspring

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