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Final TITAN results highlight apalutamide-ADT efficacy on survival in mCSPC

Final TITAN results highlight apalutamide-ADT efficacy on survival in mCSPC

Final analysis of the phase III TITAN* trial, presented at ASCO GU 2021, has shown that the addition of apalutamide to androgen deprivation therapy (ADT) improves overall survival (OS) in patients with metastatic castration-sensitive prostate cancer (mCSPC).

Final TITAN results highlight apalutamide-ADT efficacy on survival in mCSPC

Flu may trigger systemic lupus erythematosus flares

Flu may trigger systemic lupus erythematosus flares

Influenza infection appears to be a risk factor for systemic lupus erythematosus flares needing hospitalization, independently of patient age, sex, and comorbidities, a recent study has found.

Flu may trigger systemic lupus erythematosus flares

Blood biomarkers: Harbingers of heart failure, respiratory tract infections in stroke

Blood biomarkers: Harbingers of heart failure, respiratory tract infections in stroke

Blood biomarker panels prove to be useful in the prediction of two major complications of stroke, namely acute decompensated heart failure and respiratory tract infections, early after hospital admission, as shown in a study.

Blood biomarkers: Harbingers of heart failure, respiratory tract infections in stroke

Provocative testing spots treatment responders in oesophagogastric junction outflow obstruction

Provocative testing spots treatment responders in oesophagogastric junction outflow obstruction

During high-resolution oesophageal manometry (HRM), provocative testing has been shown to accurately detect clinically relevant oesophagogastric junction outflow obstruction (OGJOO) that benefits from therapy, indicating its advantage when routinely performed as part of the manometric protocol, according to a study.

Provocative testing spots treatment responders in oesophagogastric junction outflow obstruction

Regular intake of ultra-processed food ups risk of CVD, all-cause mortality

Regular intake of ultra-processed food ups risk of CVD, all-cause mortality

High consumption of ultra-processed food (UPF) may result in a heightened risk of cardiovascular disease (CVD) and all-cause mortality, driven partly by its high sugar content, according to a study.

Regular intake of ultra-processed food ups risk of CVD, all-cause mortality

Antihypertensives use tied to thinner average retinal nerve fibre layer

Antihypertensives use tied to thinner average retinal nerve fibre layer

Use of two or more antihypertensive medications, angiotensin-converting enzyme inhibitor (ACEI), and diuretics appears to induce a loss of structural markers of retinal ganglion cell health in a multiethnic Asian population, suggests a study.

Antihypertensives use tied to thinner average retinal nerve fibre layer

Antibodies work against COVID-19 D614G variant

Antibodies work against COVID-19 D614G variant

The body is capable of mounting a humoral immune response with functional cross-reactivity against the D614G variant of SARS-CoV-2, claims a recent Singapore study.

Antibodies work against COVID-19 D614G variant

Severe asthma patients on biologics predisposed to severe COVID-19

Severe asthma patients on biologics predisposed to severe COVID-19

Patients with severe asthma receiving treatment with biologics are more likely to contract COVID-19 and develop a severe course as compared with the general population, a study has found.

Severe asthma patients on biologics predisposed to severe COVID-19

Cataract linked to 30 chronic conditions

Cataract linked to 30 chronic conditions

People with cataract appear more likely to have other chronic conditions, a recent study has found. Cataract is also associated with multimorbidity, defined as having at least two physical and/or mental chronic conditions.

Cataract linked to 30 chronic conditions

Solriamfetol offers hope for excessive daytime sleepiness in OSA

Solriamfetol offers hope for excessive daytime sleepiness in OSA

The dopamine-norepinephrine reuptake inhibitor solriamfetol helps reduce excessive daytime sleepiness in patients with obstructive sleep apnoea (OSA), without compromising primary OSA treatment, as shown in a study.

Solriamfetol offers hope for excessive daytime sleepiness in OSA

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