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Whole-exome sequencing enhances diagnosis in young CRC patients
Whole-exome sequencing (WES) can improve diagnosis rates in young colorectal cancer (CRC) patients who show no pathogenic variants in mismatch repair (MMR) genes or in the adenomatous polyposis coli (APC) gene, reports a recent study.

Traditional dietary advice most preferred for IBS
Traditional dietary advice, gluten-free diet, and low FODMAP diet are all effective dietary approaches to reducing symptoms in patients with irritable bowel symptom (IBS), but traditional dietary advice is the pick of the bunch in terms of cost and convenience, according to a team of UK-based researchers.

Weight change in adults tied to colorectal adenoma risk
Weight loss during adulthood, particularly among overweight or obese individuals, is associated with a reduction in the risk of developing distal colorectal adenomas – a precursor to colorectal cancer, whereas weight gain increased its risk, according to findings from the PLCO* Cancer Screening Trial.

Universal HCV screening in pregnancy: A step toward reducing transmission?
Universal screening for hepatitis C virus (HCV) in pregnant individuals resulted in improved detection and a potential reduction in perinatal transmission, according to a study presented at CROI 2022.





