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Corticosteroids help prevent hearing loss, neurologic sequelae in paediatric bacterial meningitis
Children with bacterial meningitis appear to fare well with corticosteroids, which lead to a lower incidence of hearing loss and neurologic sequelae and faster resolution of fever, according to a meta-analysis.

Sofosbuvir easy on the kidneys
Use of sofosbuvir-based direct-acting antiviral regimens for treating hepatitis C virus (HCV) in clinical trial participants with chronic kidney disease (CKD) does not appear to worsen estimated glomerular filtration rate levels, according to a study. Furthermore, the drug does not appear to contribute to an increased risk of end-stage renal disease among HCV patients with CKD treated in clinical practice.

People who trust formal information source more likely to get COVID-19 jab
Among middle-aged and older adults, trust in formal sources of vaccine information, such as government agencies, is a strong predictor of willingness to get vaccinated against the coronavirus disease 2019 (COVID-19), according to a recent Singapore study.

Record-high rise in alcohol-related hepatitis during pandemic a cause for alarm
Cases of severe alcohol-related hepatitis requiring inpatient management has dramatically increased during the COVID-19 pandemic, particularly in patients aged <40 years and in women, a study has found.

Shorter antibiotic regimen enough in kids with pneumonia?
Children with non-severe community-acquired pneumonia (CAP) may benefit from a 5-day antibiotic regimen compared with the current standard regimen of 10 days, according to results of the US-based SCOUT-CAP trial.

What drives anxiety, depression in pregnant women during COVID-19?
Unemployment, difficulties regarding household finances, and a perceived decrease in general support lead to greater anxiety and depression burden in pregnant women during the coronavirus disease 2019 (COVID-19) pandemic, reports a recent meta-analysis.

Revised guideline for severe dengue averts death, but not organ failure
Following the revised guideline for severe dengue (SD), which includes intensive monitoring of vital signs among others, helps prevent death of patients with multiorgan failure and/or abdominal compartment syndrome (ACS), but not organ failure, a study has shown.


