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Oral corticosteroids confer little to no GDM risk for expectant mothers

05 Dec 2025 by

Exposure to oral corticosteroids during pregnancy is not associated with the risk of gestational diabetes mellitus (GDM), except for a modest increase during an early exposure window, as shown in a study from South Korea.

Oral corticosteroids confer little to no GDM risk for expectant mothers

05 Dec 2025

Relapse higher in HBeAg- patients after cessation of TAF vs TDF, entecavir

04 Dec 2025

Patients who discontinue tenofovir alafenamide (TAF) therapy appear to have a higher hepatitis B virus relapse rate than those who ceased entecavir or tenofovir disoproxil fumarate (TDF) therapy, according to a recent study.

Relapse higher in HBeAg- patients after cessation of TAF vs TDF, entecavir

04 Dec 2025

Does aspirin use worsen IBD severity in pregnant women?

04 Dec 2025

The use of aspirin among pregnant patients with inflammatory bowel disease (IBD) does not appear to increase the risk of disease severity, reports a study. Low-dose aspirin (LDA) has been prescribed to nearly a third of IBD patients during pregnancy.

Does aspirin use worsen IBD severity in pregnant women?

04 Dec 2025

Ipatasertib shows promising activity against AKT1E17K-mutant tumours

04 Dec 2025

Treatment with the pan-AKT inhibitor ipatasertib appears to induce response in patients with tumours harbouring AKT1E17K mutations, according to a study.

Ipatasertib shows promising activity against AKT1E17K-mutant tumours

04 Dec 2025

Switching to DTG/3TC or continuing B/F/TAF tied to similar virologic efficacy in adults with HIV

04 Dec 2025 by

Switching to dolutegravir/lamivudine (DTG/3TC) or continuing bictegravir/emtricitabine/tenofovir alafenamide (B/F/TAF) showed comparable virologic efficacy through 96 weeks in adults with HIV infection, according to the DYAD observational, open-label extension (OLE) study presented at IDWeek 2025.

Switching to DTG/3TC or continuing B/F/TAF tied to similar virologic efficacy in adults with HIV

04 Dec 2025

Retatrutide delivers superior weight loss in adults with obesity

03 Dec 2025

Treatment with retatrutide demonstrates superiority over GLP-1 receptor agonists (RAs) and dual agonists (GLP-1 RAs/GIP or GCGR) in terms of weight loss in adults with overweight or obesity, but it also results in a greater risk of adverse events (AEs), according to a study.

Retatrutide delivers superior weight loss in adults with obesity

03 Dec 2025

Colchicine may lower risk of arthroplasty in gout patients

02 Dec 2025

Among patients with gout, colchicine users appear to have a modestly reduced risk of total joint arthroplasty, as shown in a study.

Colchicine may lower risk of arthroplasty in gout patients

02 Dec 2025

Polypharmacy prevalent in older adults with IBD

02 Dec 2025 by

Polypharmacy appears common and tends to increase with age in patients with inflammatory bowel disease (IBD), reveals a study.

Polypharmacy prevalent in older adults with IBD

02 Dec 2025

Pharmacist care may reduce hospitalizations in HF patients

02 Dec 2025

Pharmacist interventions in heart failure (HF) across in- and outpatient settings can help lower all-cause and HF hospitalizations, according to a study.

Pharmacist care may reduce hospitalizations in HF patients

02 Dec 2025

Tenapanor relieves constipation in ESKD patients with hyperphosphataemia

02 Dec 2025 by

Individuals with end-stage kidney disease (ESKD) who have mild-to-severe constipation obtain relief from tenapanor in the post hoc analysis of the phase III BLOCK study.

Tenapanor relieves constipation in ESKD patients with hyperphosphataemia

02 Dec 2025

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Oral corticosteroids confer little to no GDM risk for expectant mothers

Oral corticosteroids confer little to no GDM risk for expectant mothers

Relapse higher in HBeAg- patients after cessation of TAF vs TDF, entecavir

Relapse higher in HBeAg- patients after cessation of TAF vs TDF, entecavir

Does aspirin use worsen IBD severity in pregnant women?

Does aspirin use worsen IBD severity in pregnant women?

Ipatasertib shows promising activity against AKT1E17K-mutant tumours

Ipatasertib shows promising activity against AKT1E17K-mutant tumours

Switching to DTG/3TC or continuing B/F/TAF tied to similar virologic efficacy in adults with HIV

Switching to DTG/3TC or continuing B/F/TAF tied to similar virologic efficacy in adults with HIV

Retatrutide delivers superior weight loss in adults with obesity

Retatrutide delivers superior weight loss in adults with obesity

Colchicine may lower risk of arthroplasty in gout patients

Colchicine may lower risk of arthroplasty in gout patients

Polypharmacy prevalent in older adults with IBD

Polypharmacy prevalent in older adults with IBD

Pharmacist care may reduce hospitalizations in HF patients

Pharmacist care may reduce hospitalizations in HF patients

Tenapanor relieves constipation in ESKD patients with hyperphosphataemia

Tenapanor relieves constipation in ESKD patients with hyperphosphataemia