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S1PRM safe, efficacious in severe UC

12 Sep 2024

Use of sphingosine 1-phosphate receptor modulators (S1PRM) demonstrates safety and efficacy in the treatment of moderate-to-severe ulcerative colitis (UC), results of a recent study have shown.

S1PRM safe, efficacious in severe UC

12 Sep 2024

Low-protein diet plus exercise a boon to CKD patients

12 Sep 2024 by

A low-protein diet (LPD) combined with physical exercise provides significant benefits to patients with chronic kidney disease (CKD) by lowering blood pressure (BP) and improving glomerular filtration and cardiopulmonary function status, a study has shown.

Low-protein diet plus exercise a boon to CKD patients

12 Sep 2024

Obesity drives malignant progression of Barrett’s esophagus

12 Sep 2024

The risk of malignant progression in individuals with Barrett’s esophagus appears to be heightened among those with obesity, with the risk increase commensurate with BMI, according to the results of a meta-analysis.

Obesity drives malignant progression of Barrett’s esophagus

12 Sep 2024

Risankizumab induction, maintenance therapy improves clinical remission in UC

10 Sep 2024 by

Induction and maintenance treatment with risankizumab significantly improved the rates of clinical remission in adults with moderate-to-severe active ulcerative colitis (UC), according to two phase III randomized clinical trials.

Risankizumab induction, maintenance therapy improves clinical remission in UC

10 Sep 2024

EUS-RV as good as precut sphincterotomy in difficult biliary cannulation

04 Sep 2024

Endoscopic ultrasound (US)-guided rendezvous (EUS-RV) technique is on a par with precut sphincterotomy as a salvage technique for patients with difficult bile duct cannulation for benign biliary disease, a study has shown. The complications rates for the two approaches are both acceptable.

EUS-RV as good as precut sphincterotomy in difficult biliary cannulation

04 Sep 2024

World’s first teleoperated magnetic endoscopy performed in an animal model

04 Sep 2024 by

Surgeons at the Chinese University of Hong Kong (CUHK) and the Swiss Federal Institute of Technology Zurich (ETH Zurich) have become the first in the world to perform teleoperated magnetic endoscopy in a porcine model across a distance of 9,300 km.

World’s first teleoperated magnetic endoscopy performed in an animal model

04 Sep 2024

Tacrolimus use linked to acute pancreatitis

03 Sep 2024

A safety signal for acute pancreatitis among users of the calcineurin inhibitor (CNI) tacrolimus has been identified in an observational retrospective pharmacovigilance study.

Tacrolimus use linked to acute pancreatitis

03 Sep 2024

In Asia, being heavier takes a toll on CRC incidence, mortality

02 Sep 2024 by

A strong, positive link between BMI and the risk of colorectal cancer (CRC) incidence and related deaths has been found in Asian populations.

In Asia, being heavier takes a toll on CRC incidence, mortality

02 Sep 2024

NALIRIFOX improves survival in older patients with mPDAC

31 Aug 2024 by

Treatment with liposomal irinotecan plus 5-fluorouracil, leucovorin, and oxaliplatin (NALIRIFOX) improved overall survival (OS) and progression-free survival (PFS) in patients aged ≥65 years with metastatic pancreatic ductal adenocarcinoma (mPDAC) compared with gemcitabine plus nab-paclitaxel (Gem+NabP), according to a post hoc analysis of the phase III NAPOLI 3 trial presented at ESMO GI 2024.

NALIRIFOX improves survival in older patients with mPDAC

31 Aug 2024

Original New Drug Application Approvals by US FDA (1-15 August 2024)

30 Aug 2024

New drug applications approved by US FDA as of 1-15 August 2024 which includes New Molecular Entities (NMEs) and new biologics. It does not include Tentative Approvals. Supplemental approvals may have occurred since the original approval date.

Original New Drug Application Approvals by US FDA (1-15 August 2024)

30 Aug 2024

News & Updates

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S1PRM safe, efficacious in severe UC

S1PRM safe, efficacious in severe UC

Low-protein diet plus exercise a boon to CKD patients

Low-protein diet plus exercise a boon to CKD patients

Obesity drives malignant progression of Barrett’s esophagus

Obesity drives malignant progression of Barrett’s esophagus

Risankizumab induction, maintenance therapy improves clinical remission in UC

Risankizumab induction, maintenance therapy improves clinical remission in UC

EUS-RV as good as precut sphincterotomy in difficult biliary cannulation

EUS-RV as good as precut sphincterotomy in difficult biliary cannulation

World’s first teleoperated magnetic endoscopy performed in an animal model

World’s first teleoperated magnetic endoscopy performed in an animal model

Tacrolimus use linked to acute pancreatitis

Tacrolimus use linked to acute pancreatitis

In Asia, being heavier takes a toll on CRC incidence, mortality

In Asia, being heavier takes a toll on CRC incidence, mortality

NALIRIFOX improves survival in older patients with mPDAC

NALIRIFOX improves survival in older patients with mPDAC

Original New Drug Application Approvals by US FDA (1-15 August 2024)

Original New Drug Application Approvals by US FDA (1-15 August 2024)