News & Updates

Use of oral antimicrobial prophylaxis with a single oral dose of ornidazole 1 g as an adjunct to intravenous antibiotic prophylaxis results in lower rates of surgical site infection within 30 days following elective colorectal surgery than with placebo, results of a multicentre trial have shown.

Prophylactic use of methylprednisolone does not appear to improve outcomes in infants undergoing cardiopulmonary bypass, even posing an increased risk of hyperglycaemia that requires insulin treatment, according to a study.

New drug applications approved by US FDA as of 01 - 15 November 2022 which includes New Molecular Entities (NMEs) and new biologics. It does not include Tentative Approvals. Supplemental approvals may have occurred since the original approval date.

The number of opioid prescriptions after surgery among older people has remained constant over a period of 7 years, although the doses have dropped, owing to a shift from fixed-dose combination towards separate opioid and nonopioid prescriptions, according to a study presented at the Anesthesiology 2022 Annual Meeting.

The prevalence of opioid misuse is declining overall, but this does not seem to be the case among nonheterosexuals, who have greater levels of abuse compared with heterosexuals, results of a study presented at the Anesthesiology Annual Meeting 2022 have shown.