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Combined oral contraceptives and VTE: Which pill conveys the highest risk in young women?
Combined oral contraceptives (COCs) that contain gestodene confer a fivefold increased risk of venous thromboembolism (VTE) in young women as compared with those that contain levonorgestrel and the lowest doses of ethinylestradiol, as shown in a study.

Add-on pembrolizumab–tocilizumab combo reduces hospitalization period in severe COVID-19
In the treatment of patients with severe COVID-19, adding the combination of pembrolizumab plus tocilizumab to standard of care (SOC) appears to result in higher and faster discharge from the hospital without sequelae, as shown in the proof-of-concept phase II COPERNICO trial.

Dulaglutide safely controls glucose in T2D with CKD
In patients with type 2 diabetes (T2D) with chronic kidney disease (CKD), once-weekly dosage with dulaglutide achieves adequate glycaemic control along with a reduced decline in estimated glomerular filtration rate (eGFR), reports a recent study.

Early transition to oral antimicrobials prevents treatment failure in children with SAB, AHO
Children with Staphylococcus aureus bacteraemia (SAB), a common complication of acute hematogenous osteomyelitis (AHO), are vulnerable to a wide range of illnesses, suggests a study. Thus, classifying its severity may aid in treatment decision-making.





