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Conjugated estrogens/bazedoxifene use tied to higher rates of endometrial cancer, hyperplasia

21 Jul 2023

In the first years of use, conjugated estrogens/bazedoxifene (CE/BZA) appears to be associated with slightly higher rates of endometrial cancer and endometrial hyperplasia compared with estrogen/progestin (EP) combination hormone therapy, according to a study.

Conjugated estrogens/bazedoxifene use tied to higher rates of endometrial cancer, hyperplasia

21 Jul 2023

Adverse neurodevelopmental outcomes higher in complicated twins

20 Jul 2023 by

Survivors of complicated monochorionic diamniotic (MCDA) twin pregnancies (ie, complicated twins) have a higher rate of adverse neurodevelopmental outcomes compared with uncomplicated twins, suggests a study presented at RCOG 2023.

Adverse neurodevelopmental outcomes higher in complicated twins

20 Jul 2023

Major malformation risk after assisted reproductive treatment higher with ICSI vs IVF

16 Jul 2023

Children conceived via fresh intracytoplasmic sperm injection (ICSI) are at higher risk of major malformations compared with those conceived via fresh in vitro fertilization (IVF), according to a study.

Major malformation risk after assisted reproductive treatment higher with ICSI vs IVF

16 Jul 2023

Higher SUA to creatinine ratio ups risk of pre-eclampsia, adverse pregnancy outcomes

14 Jul 2023

During pregnancy, a higher serum uric acid (SUA) to creatinine (sCr) ratio appears to elevate the risk of pre-eclampsia (PE) and adverse pregnancy outcomes, suggests a recent study.

Higher SUA to creatinine ratio ups risk of pre-eclampsia, adverse pregnancy outcomes

14 Jul 2023

Tranexamic acid use before CS reduces blood loss

14 Jul 2023 by

The use of prophylactic tranexamic acid (TXA) prior to elective Caesarean section (CS) led to significantly lower blood loss in women, particularly those at high risk for postpartum haemorrhage (PPH), according to a study presented at RCOG 2023.

Tranexamic acid use before CS reduces blood loss

14 Jul 2023

Mirvetuximab soravtansine improves survival in platinum-resistant ovarian cancer

13 Jul 2023 by

Treatment with mirvetuximab soravtansine, an antibody-drug conjugate (ADC) targeting folate receptor-alpha (FRα), led to significantly better survival outcomes in women with platinum-resistant ovarian cancer (PROC) compared with the investigator’s choice of chemotherapy, according to the MIRASOL trial presented at ASCO 2023.

Mirvetuximab soravtansine improves survival in platinum-resistant ovarian cancer

13 Jul 2023

KEYNOTE-826: Sustained survival benefit with pembro + chemo in advanced cervical cancer

11 Jul 2023 by

The addition of pembrolizumab immunotherapy to chemotherapy, either with or without bevacizumab, continues to confer survival benefit in patients with persistent, recurrent, or metastatic cervical cancer, regardless of their programmed death-ligand 1 (PD-L1) combined positive score (CPS), according to the updated results of the KEYNOTE-826 trial presented at ASCO 2023.

KEYNOTE-826: Sustained survival benefit with pembro + chemo in advanced cervical cancer

11 Jul 2023

Low-glycaemic index foods help improve outcomes in women at high risk of GDM

08 Jul 2023

Women who are at high risk of gestational diabetes mellitus (GDM) appear to benefit from having a low-glycaemic index (GI) or low glycaemic load diet, with a recent study showing that such a diet can control maternal weight gain and reduce the incidence of adverse neonatal outcomes.

Low-glycaemic index foods help improve outcomes in women at high risk of GDM

08 Jul 2023

Vibrating crib reduces dependence on medications in babies with prenatal opioid exposure

07 Jul 2023 by

A crib mattress that periodically vibrates may reduce the severity of withdrawal symptoms in newborns with prenatal opioid exposure and, in turn, lower the need for drug treatment, a study has shown.

Vibrating crib reduces dependence on medications in babies with prenatal opioid exposure

07 Jul 2023

Subsequent pregnancies in women with peripartum cardiomyopathy tied to adverse events

07 Jul 2023

Subsequent pregnancies (SSPs) may lead to adverse outcomes in women with peripartum cardiomyopathy (PPCM), reveals a study, noting that the normalization of left ventricular function is not an assurance for a positive outcome in SSPs.

Subsequent pregnancies in women with peripartum cardiomyopathy tied to adverse events

07 Jul 2023

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Conjugated estrogens/bazedoxifene use tied to higher rates of endometrial cancer, hyperplasia

Conjugated estrogens/bazedoxifene use tied to higher rates of endometrial cancer, hyperplasia

Adverse neurodevelopmental outcomes higher in complicated twins

Adverse neurodevelopmental outcomes higher in complicated twins

Major malformation risk after assisted reproductive treatment higher with ICSI vs IVF

Major malformation risk after assisted reproductive treatment higher with ICSI vs IVF

Higher SUA to creatinine ratio ups risk of pre-eclampsia, adverse pregnancy outcomes

Higher SUA to creatinine ratio ups risk of pre-eclampsia, adverse pregnancy outcomes

Tranexamic acid use before CS reduces blood loss

Tranexamic acid use before CS reduces blood loss

Mirvetuximab soravtansine improves survival in platinum-resistant ovarian cancer

Mirvetuximab soravtansine improves survival in platinum-resistant ovarian cancer

KEYNOTE-826: Sustained survival benefit with pembro + chemo in advanced cervical cancer

KEYNOTE-826: Sustained survival benefit with pembro + chemo in advanced cervical cancer

Low-glycaemic index foods help improve outcomes in women at high risk of GDM

Low-glycaemic index foods help improve outcomes in women at high risk of GDM

Vibrating crib reduces dependence on medications in babies with prenatal opioid exposure

Vibrating crib reduces dependence on medications in babies with prenatal opioid exposure

Subsequent pregnancies in women with peripartum cardiomyopathy tied to adverse events

Subsequent pregnancies in women with peripartum cardiomyopathy tied to adverse events