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Change in serum marker levels tied to outcomes of RA-related interstitial lung disease
In rheumatoid arthritis-related interstitial lung disease (RA-ILD), change over time in the levels of serum proteins, such as matrix metallopeptidase 13 (MMP13) and C-X-C motif ligand chemokine 11 (CXCL11), predict clinical outcomes, a recent study has found. The same is true for baseline clinical factors such as patient age and rheumatoid factor.
Bimekizumab shows promise across the spectrum of axial spondyloarthritis
Treatment with bimekizumab, a monoclonal IgG1 antibody that selectively inhibits interleukin (IL)-17F and IL-17A, significantly improved ASAS40* response rate in patients with either nonradiographic axial spondyloarthritis (nr-axSpA) or ankylosing spondylitis (AS**), according to two phase III studies presented at EULAR 2022.
Familiarity with EuroLupus dosing for cSLE remains low despite uptick in use
Paediatric specialists now use low-dose EuroLupus cyclophosphamide (CYC) more than they did a decade ago in the treatment of childhood-onset systemic lupus erythematosus (cSLE), reports a study in North America. However, familiarity with EuroLupus dosing is still low.
Limited health literacy tied to low knowledge on SLE
Limited health literacy among patients with systemic lupus erythematosus (SLE) contributes to lower knowledge about the disease, a study has shown. The Lupus Knowledge Assessment Test (LKAT) may be improved and used as a screening tool to identify those with knowledge gaps.
