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Dose-capping chemoradiotherapy tied to higher recurrence in rectal cancer
The risk of disease recurrence is increased among rectal cancer patients treated with dose-capped chemoradiotherapy (CRT), reveals a study. In addition, excessive toxicity has occurred among those dosed by actual body surface area (BSA) compared to patients in the dose-capped group.

Prompt antibiotic treatment prevents surgery in preseptal, orbital cellulitis
Differential diagnosis of preseptal and orbital cellulitis show “extremely sensitive” clinical presentation and C-reactive protein (CRP), according to a study, noting that prompt initiation of intravenous antibiotics is required and helps prevent surgical procedures even in those with incipient abscesses.

Health status similar between sacubitril/valsartan and ramipril recipients post-acute MI
Patients who receive sacubitril-valsartan after an acute myocardial infarction (MI) have a similar health status, as determined by EQ-5D visual analog scale (VAS) score, compared with those who receive ramipril, according to results of a prespecified analysis of the PARADISE-MI trial presented at HFSA 2021.






