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Dual inhibition of LAG-3, PD-1: a new therapeutic target for advanced melanoma?
In the phase II/III RELATIVITY-047 trial evaluating dual checkpoint inhibition for advanced melanoma, a new fixed-dose combination comprising the LAG-3 inhibitor relatlimab and the PD-1 inhibitor nivolumab fared better than nivolumab monotherapy.

Microneedle technology on par with topical steroids in nail psoriasis treatment
A novel transdermal device for the delivery of triamcinolone demonstrates efficacy comparable to that of conventional topical steroids in the treatment of nail psoriasis, according to a Singapore study.

Reaction patterns may aid in diagnosis of COVID-19 vaccine-related cutaneous side effects
A registry-based study has recently shown diverse COVID-19 vaccine-associated dermatologic reactions, including papulovesicular, pityriasis rosea-like, and papulosquamous eruptions classified as vaccine-related eruption of papules and plaques (V-REPP).

Depression rife in hidradenitis suppurativa
The prevalence of depression is relatively high among children, adolescents, and adults with hidradenitis suppurativa (HS), a chronic inflammatory skin disorder, according to a study, which also notes the importance of periodic screening for depression.




