News & Updates

The addition of sotorasib to panitumumab significantly improves progression-free survival (PFS) in patients with chemorefractory KRAS G12C-mutated metastatic colorectal cancer (CRC) compared with the investigator’s choice of standard-of-care (SoC) treatment, according to the CodeBreaK 300 trial presented at ESMO Asia 2023.

The risk of osteoporotic fracture seems greater in patients with autoimmune hepatitis (AIH), reveals a recent study. In addition, those with cirrhosis and long-term use of glucocorticoids appear to be at much greater risk.

It is safe to use long-term growth hormone (GH) therapy in patients with decompensated cirrhosis (DC), suggests a study, noting improvements in malnutrition and even quality of life (QoL). However, 12-month survival does not seem to improve.

Endoscopic full-thickness resection (EFTR) using a full-thickness resection device (FTRD) results in acceptable complete (R0) resection rates and low recurrence rates with a good safety profile, according to the results of a systematic review and meta-analysis.

Proton pump inhibitor (PPI) co-therapy appears to lower the risk of hospitalization for upper gastrointestinal bleeding (UGIB) in atrial fibrillation (AF) patients receiving direct oral anticoagulant (DOAC) treatment, according to a study from Korea.

Higher red meat intake is linked to a higher risk of ulcerative colitis (UC) flare, according to an expert who presented findings from a recent study at AIBD 2023.

Prior to upper gastrointestinal endoscopy, premedication with pronase helps achieve better mucosal visibility and reduce flushing frequency and volume, reports a study. However, this strategy does not appear to improve lesion detection rates.