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Second bDMARD after failure of non-TNFi biologic in RA shows modest drug survival, response

Second bDMARD after failure of non-TNFi biologic in RA shows modest drug survival, response

14 Oct 2021
Smoking reduces effect of methotrexate-based treatment in RA patients

Smoking reduces effect of methotrexate-based treatment in RA patients

14 Oct 2021

Current smoking reduces the response of patients with early rheumatoid arthritis (RA) to methotrexate (MTX) in a dose-responsive manner, regardless of concomitant prednisone use, a recent study has found.

Smoking reduces effect of methotrexate-based treatment in RA patients

14 Oct 2021
Common, cheap osteoporosis drug promising for T2D

Common, cheap osteoporosis drug promising for T2D

14 Oct 2021 byElvira Manzano

The osteoporosis drug alendronate halves the risk of developing type 2 diabetes (T2D) in a nationwide, retrospective, case-control study of nearly 700,000 patients from Denmark.

Common, cheap osteoporosis drug promising for T2D

14 Oct 2021
POETYK trials highlight potential of novel drug for plaque psoriasis

POETYK trials highlight potential of novel drug for plaque psoriasis

11 Oct 2021
Study identifies risk factors for impaired BNT162b2 mRNA antibody response in lupus

Study identifies risk factors for impaired BNT162b2 mRNA antibody response in lupus

11 Oct 2021

Among systemic lupus erythematosus patients, SARS-CoV-2-specific immune responses after BNT162b2 vaccination seem to be impaired in the presence of poor baseline humoral immune status, low naïve B cell frequencies, and mycophenolate mofetil (MMF) and methotrexate (MTX) use, according to a study.

Study identifies risk factors for impaired BNT162b2 mRNA antibody response in lupus

11 Oct 2021
Long-term KEEPsAKE data show sustained improvements with risankizumab for PsA

Long-term KEEPsAKE data show sustained improvements with risankizumab for PsA

08 Oct 2021 byAudrey Abella

The humanized immunoglobulin G1 monoclonal antibody risankizumab conferred long-term benefit for individuals with active psoriatic arthritis (PsA) who had inadequate responses to biologic and conventional synthetic DMARDs* (csDMARDs), according to the open-label extension (OLE) phase findings of the KEEPsAKE 1 and 2 trials presented at EADV 2021.

Long-term KEEPsAKE data show sustained improvements with risankizumab for PsA

08 Oct 2021
Systemic diseases, smoking history linked to more severe dry eye signs

Systemic diseases, smoking history linked to more severe dry eye signs

07 Oct 2021 byStephen Padilla

Certain systemic diseases, such as Sjögren syndrome (SS), facial rosacea, rheumatoid arthritis (RA), and peripheral artery disease, and a history of daily cigarette smoking are significantly associated with more severe dry eye disease (DED) signs, a study has found.

Systemic diseases, smoking history linked to more severe dry eye signs

07 Oct 2021