News & Updates

Short sleep implicated in colorectal adenoma risk

Colorectal adenomas, both advanced and nonadvanced, appear to be prevalent among individuals with short sleep duration, according to a study in a Vietnamese population.

AI fails to improve colonoscopic detection of advanced neoplasias

Colonoscopy assisted by artificial intelligence (AI) does not seem to enhance the detection of advanced colorectal neoplasias, according to a study.

Divarasib yields durable response across KRAS G12C-positive tumours

The covalent KRAS G12C inhibitor divarasib shows durable antitumour activity in patients harbouring KRAS G12C-positive tumours, with mostly low-grade adverse events, as shown in the phase I GO42144 study.

Add-on pembrolizumab ups survival in advanced HER2-negative G/GEJ cancer

Adding pembrolizumab to chemotherapy significantly improved survival outcomes and response rate compared with chemo alone in patients with locally advanced or metastatic HER2-negative gastric or gastroesophageal junction (G/GEJ) adenocarcinoma, according to the updated results of the KEYNOTE-859 study presented at ESMO WCGIC 2023.

Silymarin; Chronic Liver Disease; Fatty Liver Disease

Can stool test detect GI cancers?

In a prospective study from China, a novel noninvasive stool DNA methylation assay showed promise for the early detection of multiple gastrointestinal (GI) cancers.

HIMALAYA: Long-term OS benefit with STRIDE regimen in uHCC

Treatment with tremelimumab plus durvalumab (STRIDE* regimen) continues to yield overall survival (OS) benefit at 4 years among patients with unresectable hepatocellular carcinoma (uHCC) compared with sorafenib, according to the updated results of the HIMALAYA trial presented at ESMO WCGIC 2023.