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Setmelanotide lowers BMI in patients with hypothalamic obesity
Treatment with setmelanotide results in significant BMI reductions in individuals with acquired hypothalamic obesity compared with placebo, with an acceptable safety profile, as shown by the results of a phase III study presented at ENDO 2025.
Setmelanotide lowers BMI in patients with hypothalamic obesity
20 Aug 2025
CSP vs BVP: Which one is better for HFrEF with non-LBBB?
In a meta-analysis comparing procedural and clinical outcomes between conduction system pacing (CSP) and biventricular cardiac resynchronization pacing (BVP), the former appears to outdo the latter for managing individuals with heart failure with reduced ejection fraction (HFrEF) without left bundle branch block (LBBB).
CSP vs BVP: Which one is better for HFrEF with non-LBBB?
20 Aug 2025
Can pregnant, lactating people use lenacapavir to prevent HIV infection?
The use of lenacapavir is highly efficacious in pregnant and lactating people (PLP), with zero participants acquiring HIV, as shown by the results of the PURPOSE 1 study.
Can pregnant, lactating people use lenacapavir to prevent HIV infection?
19 Aug 2025
Can fasting and a no-sugar diet alleviate long COVID symptoms?
In a crossover trial evaluating the effect of two intermittent fasting (IF) regimens on long COVID (LC) symptoms, a daily 16-h fast with water-only fast and a no-sugar diet fared better than a daily 14-h time-restricted eating (TRE) regimen for mitigating long COVID symptoms.