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The selective serotonin reuptake inhibitor fluoxetine appears to modify lipid profile in individuals with overweight or obesity, with triglyceride levels reduced and high-density lipoprotein cholesterol (HDL-C) levels increased, according to a systematic review and meta-analysis.
The biosimilar BAT2206 demonstrates similar efficacy, safety, pharmacokinetics, and immunogenicity to its reference drug, ustekinumab (UST), in a recent phase III trial.
Phenobarbital (PHB) may be used if patients remain in uncontrolled alcohol withdrawal syndrome (AWS) following treatment with benzodiazepines (BZD), suggests a study.
In the treatment of children hospitalized with pneumococcal meningitis, administering dexamethasone within 12 hours of initiating antibiotics appears reduce the 30-day risk of death, according to a retrospective study.
Age and chloride level tend to contribute to the development of acute kidney injury (AKI) in traumatic brain injury (TBI) patients treated with hypertonic saline (HTS), a study has shown.
The use of triptans and combinations of this drug appears to be better than NSAIDs and acetaminophen alone in relieving pain among individuals with acute attacks of episodic migraine, reports a study.
The use of lebrikizumab improves the symptoms of moderate-to-severe atopic dermatitis (AD) in patients previously treated with dupilumab, reports a study presented at AAD 2025.
Pregnant women with inflammatory bowel disease (IBD), especially those with thiopurine exposure, face a heightened risk of intrahepatic cholestasis of pregnancy (ICP), according to the results of a systematic review and meta-analysis.
Treatment with remibrutinib, an oral, highly selective Bruton’s tyrosine kinase inhibitor, improved sleep and daily activities in patients with chronic spontaneous urticaria (CSU), according to two phase III REMIX-1 and -2 studies presented at AAD 2025.
Treatment with sacubitril-valsartan (SV) demonstrates good tolerability and may provide some benefits to hypertension patients with end-stage kidney disease (ESKD) who are undergoing dialysis, as shown by the results of a recent meta-analysis.
