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COVID-19 lockdown weakens metabolism in people with glucose intolerance

COVID-19 lockdown weakens metabolism in people with glucose intolerance

10 Sep 2022

In Japan, the declaration of a state of emergency in response to the COVID-19 pandemic led to negative metabolic consequences in people with glucose intolerance, such as lowered skeletal muscle and increased body weight and body fat, a recent study has found.

COVID-19 lockdown weakens metabolism in people with glucose intolerance

10 Sep 2022
Trifluridine/tipiracil add-on to bevacizumab safe, effective for mCRC

Trifluridine/tipiracil add-on to bevacizumab safe, effective for mCRC

09 Sep 2022

In patients with metastatic colorectal cancer (mCRC), using trifluridine/tipiracil with bevacizumab is a safe and effective treatment for refractory disease, a recent study has found.

Trifluridine/tipiracil add-on to bevacizumab safe, effective for mCRC

09 Sep 2022
Low-dose methotrexate-related melanoma risk considered negligible

Low-dose methotrexate-related melanoma risk considered negligible

09 Sep 2022
Nine metabolic biomarkers can detect gastric cancer

Nine metabolic biomarkers can detect gastric cancer

09 Sep 2022 byTristan Manalac

Gastric cancer (GC) patients show an altered metabolic profile as compared with healthy individuals, a recent China study has found. A biomarker panel monitoring for nine metabolites can facilitate timely detection of GC.

Nine metabolic biomarkers can detect gastric cancer

09 Sep 2022
CROWN: 1L lorlatinib improves PFS, reduces CNS progression in ALK-positive NSCLC ± brain metastases

CROWN: 1L lorlatinib improves PFS, reduces CNS progression in ALK-positive NSCLC ± brain metastases

09 Sep 2022 bySarah Cheung

First-line treatment of ALK-positive non-small-cell lung cancer (NSCLC) with lorlatinib improves progression-free survival (PFS) and reduces central nervous system (CNS) progression vs crizotinib, regardless of presence or absence of baseline brain metastases (BM), a post hoc analysis of the phase III CROWN trial has shown.

CROWN: 1L lorlatinib improves PFS, reduces CNS progression in ALK-positive NSCLC ± brain metastases

09 Sep 2022