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SGLT2 inhibitors help ward off asthma
Patients on sodium-glucose co-transporter (SGLT) 2 inhibitors are less likely to develop asthma compared with those on dipeptidyl peptidase (DPP)-4 inhibitors and glucagon-like peptide-1 receptor agonists (GLP-1RAs), a study has found.
SGLT2 inhibitors help ward off asthma
12 Oct 2021
Tamibaroterone inhalable dry powder shows broad-spectrum activity against SARS-CoV-2, MERS and H1N1
Researchers from the University of Hong Kong (HKU) have developed a dry powder formulation of tamibaroterone, which displays broad-spectrum antiviral activity against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), Middle East respiratory syndrome coronavirus (MERS-CoV), and pandemic 2009 influenza A virus (H1N1), when delivered intranasally or through inhalation in mouse and hamster models.
Tamibaroterone inhalable dry powder shows broad-spectrum activity against SARS-CoV-2, MERS and H1N1
12 Oct 2021
Households, not schools, major SARS-CoV-2 transmission route among HK children
Households, and not schools, are the major route of coronavirus disease 2019 (COVID-19) transmission for those ≤18 years of age, according to a cross-sectional study of nearly 400 Hong Kong children and youths who contracted COVID-19 in 2020.
Households, not schools, major SARS-CoV-2 transmission route among HK children
12 Oct 2021
Recovered mothers transfer SARS-CoV-2 antibodies to newborns
A Hong Kong study demonstrates vertical transfer of antibodies against acute respiratory syndrome coronavirus 2 (SARS-CoV-2) to babies whose mothers have recovered from coronavirus disease 2019 (COVID-19).
Recovered mothers transfer SARS-CoV-2 antibodies to newborns
12 Oct 2021
Early convalescent plasma infusion does not prevent COVID-19 progression
An infusion of convalescent plasma, obtained via blood donation from individuals who have recovered from COVID-19, did not prevent disease progression in high-risk outpatients who presented within 7 days of COVID-19 symptom onset, results of the phase III US-based SIREN-C3PO* study showed.
Early convalescent plasma infusion does not prevent COVID-19 progression
11 Oct 2021
Early intubation tied to better survival in COVID-19 patients with ARDS
Late intubation compounds the risk of death among coronavirus disease 2019 (COVID-19) patients on mechanical intubation due to respiratory insufficiency, a recent study has found.
Early intubation tied to better survival in COVID-19 patients with ARDS
11 Oct 2021
ACE inhibitors, ARBs put brakes on emphysema progression, lung function decline in COPD
Angiotensin converting enzyme (ACE) inhibitors and angiotensin-receptor blockers (ARBs) appear to be beneficial to chronic obstructive pulmonary disease (COPD) patients, with a recent study suggesting that the use of such drugs may slow down progression of emphysema and lung function decline.
ACE inhibitors, ARBs put brakes on emphysema progression, lung function decline in COPD
10 Oct 2021
Acid suppression drugs counteract EGFR-TKIs for NSCLC treatment
Acid suppression (AS) medications, such as proton pump inhibitors (PPIs) and histamine type-2 receptor antagonists (H2RAs), weaken the efficacy of epidermal growth factor receptor (EGFR) tyrosine kinase inhibitors (TKI) in nonsmall cell lung cancer (NSCLC), resulting in worse survival outcomes, according to a recent Singapore meta-analysis.