News & Updates

Cannabis has ceiling concentration for efficacy

14 Dec 2020

Tetrahydrocannabinol (THC) is effective in reducing pain, but only up to a certain plasma concentration, beyond which it appears to magnify pain, according to a new study.

Cannabis has ceiling concentration for efficacy

14 Dec 2020

What are the barriers to self-care of CKD?

14 Dec 2020 by

Lack of knowledge among patients, insufficient communication between doctors and patients, and lack of motivation are stumbling blocks to self-care of chronic kidney disease (CKD) in Singapore, while trust for doctors and family support can turn the tide around, a local study finds.

What are the barriers to self-care of CKD?

14 Dec 2020

Can common BP-lowering drugs keep breast cancer in check?

14 Dec 2020 by

Angiotensin receptor blockers, used to treat high blood pressure (BP), appear to confer dose-dependent survival benefits on breast cancer patients when taken either prior to or after diagnosis, a study has found.

Can common BP-lowering drugs keep breast cancer in check?

14 Dec 2020

NOACs lower renal function decline in AF patients

14 Dec 2020

A prescription of nonvitamin K antagonist (VKA) oral anticoagulants (NOACs) in patients with atrial fibrillation (AF) leads to a lower renal function worsening compared to those receiving VKAs, suggests a recent study, adding that such effect is partially lost in diabetic patients.

NOACs lower renal function decline in AF patients

14 Dec 2020

ARTEMIS 1: Bimatoprost implant noninferior to timolol in lowering IOP

14 Dec 2020 by

Bimatoprost implant of either 10- or 15-μg dose strength is noninferior to timolol through week 12 in patients with open-angle glaucoma (OAG) or ocular hypertension (OHT), according to the results of the phase III trial ARTEMIS 1.

ARTEMIS 1: Bimatoprost implant noninferior to timolol in lowering IOP

14 Dec 2020

β-blocker use improves survival in oesophageal cancer patients on chemoradiation

14 Dec 2020

Use of β-blockers results in significant survival benefits in oesophageal cancer patients receiving concurrent chemoradiation, a study has shown.

β-blocker use improves survival in oesophageal cancer patients on chemoradiation

14 Dec 2020

Upadacitinib outdoes abatacept for rheumatoid arthritis

14 Dec 2020 by

The oral selective Janus kinase (JAK) inhibitor upadacitinib was superior to IV abatacept, a T-cell costimulation modulator, for the treatment of rheumatoid arthritis (RA) that is refractory to biologic disease-modifying antirheumatic drugs (bDMARDs), the SELECT-CHOICE trial has shown.

Upadacitinib outdoes abatacept for rheumatoid arthritis

14 Dec 2020

SHIELD: Oral supplements keep malnutrition at bay in older adults

14 Dec 2020 by

Oral nutritional supplements (ONS), containing beta-hydroxy-beta-methylbutyrate (HMB) and vitamin D, when supplemented with dietary counselling, improves functional and nutritional outcomes among community-dwelling older adults, according to the recent Singapore study Strengthening Health in Elderly Through Nutrition (SHIELD).

SHIELD: Oral supplements keep malnutrition at bay in older adults

14 Dec 2020

Antimalarial agents for COVID-19 may be cardiotoxic

14 Dec 2020

Use of chloroquine and hydroxychloroquine in the treatment of COVID-19 appears to promote QT prolongation and lead to an increased incidence of events such as torsade de pointes, ventricular tachycardia, and cardiac arrest, according to a study.

Antimalarial agents for COVID-19 may be cardiotoxic

14 Dec 2020

Obesity carries greater risk of colorectal cancer in post- vs premenopausal women

14 Dec 2020

Obesity contributes to a significant increase in the risk of colorectal cancer (CRC) in postmenopausal than in premenopausal women, a study has found.

Obesity carries greater risk of colorectal cancer in post- vs premenopausal women

14 Dec 2020

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Cannabis has ceiling concentration for efficacy

Cannabis has ceiling concentration for efficacy

What are the barriers to self-care of CKD?

What are the barriers to self-care of CKD?

Can common BP-lowering drugs keep breast cancer in check?

Can common BP-lowering drugs keep breast cancer in check?

NOACs lower renal function decline in AF patients

NOACs lower renal function decline in AF patients

ARTEMIS 1: Bimatoprost implant noninferior to timolol in lowering IOP

ARTEMIS 1: Bimatoprost implant noninferior to timolol in lowering IOP

β-blocker use improves survival in oesophageal cancer patients on chemoradiation

β-blocker use improves survival in oesophageal cancer patients on chemoradiation

Upadacitinib outdoes abatacept for rheumatoid arthritis

Upadacitinib outdoes abatacept for rheumatoid arthritis

SHIELD: Oral supplements keep malnutrition at bay in older adults

SHIELD: Oral supplements keep malnutrition at bay in older adults

Antimalarial agents for COVID-19 may be cardiotoxic

Antimalarial agents for COVID-19 may be cardiotoxic

Obesity carries greater risk of colorectal cancer in post- vs premenopausal women

Obesity carries greater risk of colorectal cancer in post- vs premenopausal women