News &amp; Updates

Prostate-specific membrane antigen (PSMA) PET-CT offers superior accuracy in identifying pelvic nodal or distant-metastatic disease in men with high-risk prostate cancer and may be a suitable replacement for conventional imaging with CT combined with bone scan, according to results of the proPSMA study.

PSMA PET-CT superior to CT plus bone scan in high-risk prostate cancer

Drug–drug interactions with DOACs persist despite computerized alerts

Clinicians vary as to how they manage drug–drug interactions (DDIs) with direct oral anticoagulants (DOACs) in clinical practice, with potentially substantial DDIs with DOACs still occurring despite computerized alerts, according to a study.

Drug–drug interactions with DOACs persist despite computerized alerts

Alopecia areata bidirectionally linked to major depressive disorder

A bidirectional association exists between alopecia areata (AA) and major depressive disorder (MDD) among probands and unaffected siblings, reveals a study. This suggests that shared familial mechanisms tend to cause AA and MDD.

Alopecia areata bidirectionally linked to major depressive disorder

Pembrolizumab improves pCR in early triple-negative breast cancer

The addition of the anti-PD-1* monoclonal antibody pembrolizumab to platinum-based neoadjuvant chemotherapy (CT) led to a significant increase in the proportion of women with early triple-negative breast cancer (TNBC) who had a pathological complete response (pCR), the phase III KEYNOTE-522 trial has shown.

Pembrolizumab improves pCR in early triple-negative breast cancer

Thicker macula tied to better vision

In healthy eyes, a thicker macula and ganglion cell-inner plexiform layer (GCIPL) is associated with better visual functioning, according to a recent Singapore study.

Thicker macula tied to better vision

$Antidepressants up fracture risk in older adults$

Antidepressants up fracture risk in older adults

Antidepressants, particularly selective serotonin reuptake inhibitors (SSRIs), appear to increase the risk of fractures in older adults, a recent study has shown.

Antidepressants up fracture risk in older adults

Adjunct liraglutide therapy helps lower BMI in obese teens

Adding liraglutide to first-line lifestyle therapy led to a significantly reduced BMI standard-deviation score (BMI SDS*) among obese adolescents who failed to respond to lifestyle therapy alone, according to a study presented at ENDO 2020.

Adjunct liraglutide therapy helps lower BMI in obese teens

Coronavirus can travel up to 4 metres in air

20 Apr 2020 by

SARS-CoV-2, the virus causing COVID-19, was widely distributed on object surfaces and could spread as far as 4 metres in the air based on sampling from hospital wards in China — a distance that far exceeds the current guideline recommendations on social distancing.

Coronavirus can travel up to 4 metres in air

Basal insulin raises safety concerns in T2DM patients

Basal insulin therapy as a third antidiabetic agent appears to come with excess all-cause mortality risk in patients with type 2 diabetes mellitus (T2DM), a recent study has shown.

Basal insulin raises safety concerns in T2DM patients

Early-onset nephrolithiasis tied to frequent stone recurrences

Individuals who develop stones prior to age 20 years are at high risk of having frequent recurrences, with the risk even more pronounced in women, a study has found.

Early-onset nephrolithiasis tied to frequent stone recurrences