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Tricyclic antidepressant for IBS worth a try
15 Jan 2024
byJairia Dela Cruz
The tricyclic antidepressant amitriptyline, when used at low dose in the second-line treatment setting and titrated according to symptom response and side-effects, is safe and provides relief from symptoms of irritable bowel syndrome (IBS), as shown in the phase III ATLANTIS* trial.
Tricyclic antidepressant for IBS worth a try
15 Jan 2024Resection plus chemo improves survival in patients with UCR-MAC-LM
14 Jan 2024
byStephen Padilla
Primary tumour resection (PTR) in combination with chemotherapy (C) appears beneficial to a specific subgroup of patients with unresectable colorectal mucinous adenocarcinoma with liver metastasis (UCR-MAC-LM) compared with PTR or C alone, suggests a study.