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Sotorasib improves PFS over docetaxel in KRASG12C-mutated advanced NSCLC
The first-in-class KRASG12C inhibitor sotorasib significantly improved progression-free survival (PFS) in patients with previously treated non-small cell lung cancer (NSCLC) with KRASG12C mutations, according to results of the phase III CodeBreaK 200 trial presented at ESMO 2022.
Sotorasib improves PFS over docetaxel in KRASG12C-mutated advanced NSCLC
15 Dec 2022
Oral testosterone undecanoate safe, effective in hypogonadal men
Long-term treatment with an oral testosterone undecanoate (TU) formulation improves clinical outcomes in men with hypogonadism with no serious safety concerns, a study has shown.
Oral testosterone undecanoate safe, effective in hypogonadal men
15 Dec 2022
Antirheumatic drugs confer cardioprotection, too
Treatments used in rheumatoid arthritis, called disease-modifying antirheumatic drugs, can also lower the risk of heart disease among patients, as shown in a recent study.
Antirheumatic drugs confer cardioprotection, too
14 Dec 2022
Prophylactic G-CSF averts febrile neutropaenia in docetaxel-treated breast cancer patients
Prophylactic granulocyte-colony stimulating factor (G-CSF) results in a significant decrease both in the rate of febrile neutropaenia (FN) and duration of hospitalization for FN in breast cancer patients treated with docetaxel-based chemotherapy regimens (DBRs), according to a recent study.
Prophylactic G-CSF averts febrile neutropaenia in docetaxel-treated breast cancer patients
14 Dec 2022
Palbociclib–bazedoxifene combo for HR+/HER2− breast cancer succeeds in early trial
Treatment with the combination of palbociclib plus bazedoxifene demonstrates clinical efficacy while having an acceptable safety profile in treatment-experienced patients with hormone receptor–positive/HER2-negative (HR+/HER2−) advanced breast cancer, according to the results of a phase Ib/II study.