News &amp; Updates

Single-ventricle physiology appears to predict higher short-term mortality among adult transplant recipients with coronary heart disease (CHD), suggests a study.

Single-ventricle CHD tied to poorer survival after heart transplant

Twice-daily deferasirox effective, well-tolerated in paediatric thalassaemia patients

Treatment with deferasirox twice daily, compared with a once-daily regimen, results in significant improvements in the iron chelation efficacy and tolerability among transfusion-dependent paediatric beta-thalassaemia patients, a study has shown.

Twice-daily deferasirox effective, well-tolerated in paediatric thalassaemia patients

SLE rash treatment better with GC plus hydroxychloroquine combo vs GC monotherapy

Combination treatment with glucocorticoid (GC) plus hydroxychloroquine appears to yield more favourable outcomes than GC alone in the treatment of systemic lupus erythematosus (SLE) rash, while having a good safety profile, according to a study.

SLE rash treatment better with GC plus hydroxychloroquine combo vs GC monotherapy

16 Sep 2023

Extended clopidogrel monotherapy after DAPT reduces bleeding events in ‘bi-risk’ ACS patients

16 Sep 2023 by

Extended clopidogrel monotherapy after a 9- to 12-month course of dual antiplatelet therapy (DAPT) reduces bleeding and ischaemic events in patients with acute coronary syndrome (ACS) who are at high risk for both events, according to the OPT-BIRISK* trial presented at ESC 2023.

Extended clopidogrel monotherapy after DAPT reduces bleeding events in ‘bi-risk’ ACS patients

Common antihypertensive drug linked to glaucoma

The use of calcium channel blockers (CCBs) may contribute to an increased risk of glaucoma despite CCBs having no effect on intraocular pressure (IOP), according to a large study.

Common antihypertensive drug linked to glaucoma

Food additives up risk of CVD

Intake of additive emulsifiers, which is widely used in industrial foods, appears to increase the risk of cardiovascular disease (CVD), suggests a recent study.

Food additives up risk of CVD

15 Sep 2023

Comprehensive geriatric assessment reduces complications, mortality in vascular patients

Vascular-Geriatric Service (VGS), the first formal Geriatric Liaison Service for surgical patients in a tertiary hospital in Singapore, has resulted in a significant decrease in medical complications and 30-day mortality in older frail patients with multimorbidity, reports a study.

Comprehensive geriatric assessment reduces complications, mortality in vascular patients

Lower testosterone, increased LH levels indicate impaired testicular function in older men

Several factors contribute to the variation in male testosterone, sex hormone-binding globulin (SHBG), and luteinizing hormone (LH) concentrations, suggests a study. Moreover, reduced testosterone and elevated LH levels appear to be signs of an impaired testicular function after age 70 years.

Lower testosterone, increased LH levels indicate impaired testicular function in older men

COSMIC-313 highlights benefit of triplet regimen in RCC

In the COSMIC-313 trial, the addition of the tyrosine kinase inhibitor (TKI) cabozantinib to the immune checkpoint inhibitor (ICI)-doublet regimen comprising nivolumab and ipilimumab (NIVO/IPI) improved progression-free survival (PFS) in patients with previously untreated, advanced renal-cell carcinoma (RCC) who had intermediate or poor prognostic risk according to the IMDC* category.

COSMIC-313 highlights benefit of triplet regimen in RCC

15 Sep 2023

Stage IIIA/B NSCLC: Perioperative nivolumab plus chemo improves pCR, survival vs neoadjuvant chemo