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Switching from cetuximab to bevacizumab associated with acceptable survival, reduced derm toxicity in mCRC
Switching from FOLFIRI plus cetuximab to FOLFIRI plus bevacizumab leads to acceptable survival outcomes and a reduction in severe dermatological toxicities in patients with RAS wild-type (RASwt) metastatic colorectal cancer (mCRC), according to the results of a single-arm phase II HYBRID trial.
Switching from cetuximab to bevacizumab associated with acceptable survival, reduced derm toxicity in mCRC
23 Apr 2024Lower VTE risk seen in atopic dermatitis vs other inflammatory diseases
Atopic dermatitis (AD) does not seem to induce an increase in the risk of venous thromboembolism (VTE) when considering underlying risk factors, suggests a study. Moreover, patients with AD show a lower VTE risk than those with rheumatoid arthritis (RA), Crohn's disease (CD), ulcerative colitis (UC), psoriatic arthritis (PsA), or ankylosing spondylitis (AS).
Lower VTE risk seen in atopic dermatitis vs other inflammatory diseases
22 Apr 2024Gene profiling of skin lesions improves diagnosis of allergic contact dermatitis
Analysing molecular signatures from active skin lesions aids in the stratification of patients with contact dermatitis (CD) and helps identify those with allergic CD, suggests a study.
Gene profiling of skin lesions improves diagnosis of allergic contact dermatitis
19 Apr 2024Oral minoxidil may be a viable alternative to topical treatment for male pattern baldness
Low-dose oral minoxidil demonstrates comparable efficacy to 5% topical minoxidil in the treatment of androgenetic alopecia in men, offering a viable option for those who prefer oral therapy or those who poorly tolerate topical treatment, as shown in a study.
Oral minoxidil may be a viable alternative to topical treatment for male pattern baldness
13 Apr 2024Deuruxolitinib helps restore crowning glory in alopecia areata
Pooled analyses of the phase III THRIVEAA1 and THRIVE-AA2 trials underpin the potential of the selective oral JAK* 1/2 inhibitor deuruxolitinib to effectively and safely reverse hair loss in adults with moderate-to-severe alopecia areata (AA).