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JAK inhibitors shown safe, effective in RA patients
A recent study has demonstrated the safety and efficacy of oral Janus kinase (JAK) inhibitors in patients with rheumatoid arthritis (RA) in the real-world setting, particularly in those who do not present with cardiovascular risk factors at baseline.
JAK inhibitors shown safe, effective in RA patients
24 Jul 2024Adalimumab concentrations negatively linked to inflammatory markers in RA
A negative association exists between adalimumab (ADA) concentrations and markers of inflammatory disease activity in rheumatoid arthritis (RA), including interleukin 6 (IL-6), reveals a study. Notably, ADA concentrations from 5 to 7 mg/L over the dose interval seem to contribute to better disease control.
Adalimumab concentrations negatively linked to inflammatory markers in RA
22 Jul 2024[test headline bait]Amivantamab plus chemo tied to better outcomes in NSCLC
Treatment with amivantamab (ami) in combination with chemotherapy (chemo) results in substantially longer time to treatment discontinuation (TTD), time to subsequent therapy (TTST), and progression-free survival (PFS) after first subsequent therapy (PFS2) in patients with EGFR-mutant advanced nonsmall cell lung cancer (NSCLC) following progression on osimertinib, as shown in a postprogression analysis.