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Camostat mesylate flops against SARS-CoV-2
The serine protease inhibitor camostat mesylate does not appear to be an effective antiviral agent in patients with early-phase COVID-19, having failed to stop SARS-CoV-2 in its tracks in a phase II trial.
Camostat mesylate flops against SARS-CoV-2
12 Jul 2022Isotretinoin does not hurt patients’ mental health, study says
While treatment with isotretinoin for acne is said to have a negative impact on mental health, its use appears to instead mitigate the excess psychiatric risk associated with treatment-resistant moderate-to-severe acne, as reported in a large study.
Isotretinoin does not hurt patients’ mental health, study says
11 Jul 2022Systematic endotracheal aspiration cuts antibiotic use for ventilator-related pneumonia
Being aware of bronchial colonization results in a decreased use of initial broad-spectrum antibiotic for ventilator-associated pneumonia (VAP) in the paediatric intensive care unit (PICU), reports a recent study.
Systematic endotracheal aspiration cuts antibiotic use for ventilator-related pneumonia
11 Jul 2022Is extended superior to standard antibiotic course in children hospitalized with CAP?
An extended antibiotic course appears to be not any better than a standard course at achieving clinical cure among children hospitalized with community-acquired pneumonia (CAP) and at risk of chronic respiratory illnesses at 4 weeks, a study has shown.
Is extended superior to standard antibiotic course in children hospitalized with CAP?
11 Jul 2022Sabizabulin for metastatic castration-resistant prostate cancer clears phase early trial
The oral cytoskeleton disruptor sabizabulin shows antitumour activity in men with metastatic castration-resistant prostate cancer, while having a favourable safety profile, as shown in the results of a phase Ib/II trial.