News & Updates

Performance status, not age, predicts nivolumab efficacy, safety in elderly NSCLC patients

04 Jun 2020

Age does not appear to affect the efficacy of nivolumab for non-small cell lung cancer (NSCLC), a recent study has found. A more important factor to look at, instead, would be performance status.

Performance status, not age, predicts nivolumab efficacy, safety in elderly NSCLC patients

04 Jun 2020

Metformin prevents prednisone-induced hyperglycaemia in haematological cancers

04 Jun 2020

Use of metformin is effective in preventing hyperglycaemia in nondiabetic cancer patients exposed to high-dose prednisone-based chemotherapy, results of a randomized study have shown.

Metformin prevents prednisone-induced hyperglycaemia in haematological cancers

04 Jun 2020

Pembrolizumab not cost-effective for NSCLC in SG

03 Jun 2020 by

Pembrolizumab monotherapy shows superior efficacy to standard chemotherapy for non-small cell lung cancer (NSCLC), according to a new Singapore study. However, its current pricing in the country makes it the less economical option.

Pembrolizumab not cost-effective for NSCLC in SG

03 Jun 2020

Study reveals inverse association between breast cancer, arthritis

02 Jun 2020 by

Women with rheumatoid arthritis (RA) have a reduced risk of breast cancer; similarly, women with breast cancer have a reduced risk of RA, reveals a Swedish study. Moreover, adjuvant antihormonal therapy for breast cancer prevention does not appear to increase the risk of RA.

Study reveals inverse association between breast cancer, arthritis

02 Jun 2020

Original New Drug Application Approvals by US FDA (16 - 31 May 2020)

02 Jun 2020

New drug applications approved by US FDA as of 16 - 31 May 2020 which includes New Molecular Entities (NMEs) and new biologics. It does not include Tentative Approvals. Supplemental approvals may have occurred since the original approval date.

Original New Drug Application Approvals by US FDA (16 - 31 May 2020)

02 Jun 2020

Cancer management: A challenge in the time of COVID-19

01 Jun 2020 by

The COVID-19 pandemic has, and continues to have, a significant effect on the lives of individuals worldwide. Published reports suggest an elevated risk of COVID-19 among patients with cancer. As such, oncologists globally have had to adapt their management of cancer patients to minimize the risk of infection, while ensuring optimal care for this population.

Cancer management: A challenge in the time of COVID-19

01 Jun 2020

Adequate vitamin D, magnesium levels reduce mortality risk in colorectal cancer

01 Jun 2020 by

The combination of 25(OH)D3 and magnesium appears to lower the risk of mortality in patients with colorectal cancer (CRC), but the underlying mechanism remains to explained, suggests a study.

Adequate vitamin D, magnesium levels reduce mortality risk in colorectal cancer

01 Jun 2020

Atezolizumab + bevacizumab tops sorafenib in unresectable HCC

01 Jun 2020 by

The combination of atezolizumab and bevacizumab (atezo-bev) delivered better overall survival (OS) and progression-free survival (PFS) outcomes than sorafenib in patients with untreated, locally advanced metastatic or unresectable hepatocellular carcinoma (HCC), the phase III IMbrave150 trial has shown.

Atezolizumab + bevacizumab tops sorafenib in unresectable HCC

01 Jun 2020

Decitabine–vorinostat combo flops in paediatric B-cell acute lymphoblastic leukaemia trial

01 Jun 2020

The combination of decitabine and vorinostat does not appear to be feasible in the treatment of children with B-cell acute lymphoblastic leukaemia (B-ALL), despite encouraging response rates and pharmacodynamics, because of increased incidence of significant infectious toxicities, according to data from the TACL* pilot study.

Decitabine–vorinostat combo flops in paediatric B-cell acute lymphoblastic leukaemia trial

01 Jun 2020

Depression risk high among spouses of cancer patients

30 May 2020

Spouses of cancer patients are at an elevated risk of major depressive disorder (MDD), a new study has found.

Depression risk high among spouses of cancer patients

30 May 2020

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Performance status, not age, predicts nivolumab efficacy, safety in elderly NSCLC patients

Performance status, not age, predicts nivolumab efficacy, safety in elderly NSCLC patients

Metformin prevents prednisone-induced hyperglycaemia in haematological cancers

Metformin prevents prednisone-induced hyperglycaemia in haematological cancers

Pembrolizumab not cost-effective for NSCLC in SG

Pembrolizumab not cost-effective for NSCLC in SG

Study reveals inverse association between breast cancer, arthritis

Study reveals inverse association between breast cancer, arthritis

Original New Drug Application Approvals by US FDA (16 - 31 May 2020)

Original New Drug Application Approvals by US FDA (16 - 31 May 2020)

Cancer management: A challenge in the time of COVID-19

Cancer management: A challenge in the time of COVID-19

Adequate vitamin D, magnesium levels reduce mortality risk in colorectal cancer

Adequate vitamin D, magnesium levels reduce mortality risk in colorectal cancer

Atezolizumab + bevacizumab tops sorafenib in unresectable HCC

Atezolizumab + bevacizumab tops sorafenib in unresectable HCC

Decitabine–vorinostat combo flops in paediatric B-cell acute lymphoblastic leukaemia trial

Decitabine–vorinostat combo flops in paediatric B-cell acute lymphoblastic leukaemia trial

Depression risk high among spouses of cancer patients

Depression risk high among spouses of cancer patients