News & Updates

A clinically meaningful endpoint for future therapeutic trials in urological chronic pelvic pain syndrome is a decrease of 30‒50 percent in pelvic pain severity, suggests a study. Clinically significant differences for urinary symptom severity are more appropriately defined separately for males and females.

Treatment with 2.0-mg OPT-302, a biologic inhibitor of vascular endothelial growth factor (VEGF)-C and D, in combination with ranibizumab, an anti‒VEGF-A inhibitor, results in greater vision gains when compared with the current standard of care for neovascular age-related macular degeneration (nAMD), reports a study. In addition, the combined therapy has an acceptable safety profile.

Dietary modification (DM) among individuals in the lowest quartile for percentage calories from total fat at baseline is associated with a higher risk of incident primary open-angle glaucoma (POAG) among women, irrespective of age or race, suggests a recent study.

Adults with atopic dermatitis appear to have an increased risk of venous thromboembolism (VTE), although the risk difference relative to adults without AD is quite small, as reported in a study.

Weight regain measured as percentage of maximum weight lost (%MWL) appears to be a better predictor of postoperative glucose metabolism deterioration within 3 years than other quantifiers in patients with obesity and type 2 diabetes mellitus (T2DM) who underwent bariatric surgery, according to a China study. Of note, the optimal cutoff point is 20 percent MWL.