News & Updates

In patients with relapsed/refractory multiple myeloma (R/R MM), a combination of melflufen and dexamethasone proved better than an approved doublet standard-of-care (SoC) comprising pomalidomide-dexamethasone in terms of progression-free survival (PFS), the phase III OCEAN trial has shown. However, the overall survival (OS) outcome with the melflufen-containing regimen appeared to digress from the PFS result, potentially casting doubt on its benefit for this condition.

When used in addition to standard of care, favipiravir leads to faster viral clearance and clinical improvement time among patients hospitalized with COVID-19, although it appears to contribute to an increased risk of hyperuricaemia, according to the results of a meta-analysis

Among fixed-dose combinations of inhaled corticosteroids/long-acting beta-2-adrenergic agonists (ICS/LABA), the newer combinations of fluticasone furoate/vilanterol (FF/VI) and fluticasone propionate/formoterol (FP/FORM) are associated with increased treatment persistence and lead to fewer exacerbations among patients with asthma, as shown in a study.

The eutectic-like mixture of prilocaine/lidocaine spray appears to work well in the treatment of men with various types of premature ejaculation, as reflected by a high treatment adherence, according to data from a real-world study.