News &amp; Updates

In elderly adults with myelodysplastic syndrome (MDS), the comprehensive geriatric assessment can detect geriatric-related health issues and may be useful in identifying those unlikely to benefit from azacytidine treatment, a recent study has shown.

Comprehensive geriatric assessment may help refine azacytidine targets in MDS

Adding metformin to TKI may be detrimental to nondiabetic patients with EGFR-positive NSCLC

The concurrent use of metformin with the tyrosine kinase inhibitor (TKI) gefitinib does more harm than good, resulting in significantly worse outcomes and increasing the risk of diarrhoea in nondiabetic patients with nonsmall cell lung cancer (NSCLC) harbouring EFGR mutation, according to data from a phase II trial.

Adding metformin to TKI may be detrimental to nondiabetic patients with EGFR-positive NSCLC

Carbamazepine, lamotrigine use tied to squamous cell carcinoma

Treatment with antiepileptic drugs does not increase the risk of skin cancer, but an association has been observed between use of carbamazepine and lamotrigine and squamous cell carcinoma (SCC), a recent study has shown.

Carbamazepine, lamotrigine use tied to squamous cell carcinoma

Incomplete excision likely in poorly differentiated cSCCs

Poorly differentiated cutaneous squamous cell carcinomas (cSCCs) are likely to be incompletely excised in peripheral and deep planes, despite adherence to the British Association of Dermatology-British Association of Plastic, Reconstructive and Aesthetic Surgery guidelines, reports a recent UK study.

Incomplete excision likely in poorly differentiated cSCCs

Patients with ulcerative colitis at risk for CRC diagnosis, mortality

17 Jan 2020 by

Individuals with ulcerative colitis (UC) appear to be at an elevated risk of developing and dying from colorectal cancer (CRC), despite often presenting at an earlier stage of CRC than those without UC, a recent study showed.

Patients with ulcerative colitis at risk for CRC diagnosis, mortality

Ipilimumab with stereotactic radiotherapy feasible for metastatic cancers

The use of ipilimumab with stereotactic radiotherapy, either concurrently or sequentially, yields satisfactory outcomes with low toxicities in patients with metastatic cancer, according to the results of a phase II trial.

Ipilimumab with stereotactic radiotherapy feasible for metastatic cancers

Adherence to healthy lifestyle at mid-life extends life expectancy free of chronic diseases

17 Jan 2020 by

It is never too late to observe a healthy way of life. According to a recent study, adopting a healthy diet and lifestyle at mid-life can still lead to a longer life expectancy free of major chronic diseases.

Adherence to healthy lifestyle at mid-life extends life expectancy free of chronic diseases